云南高校图书馆联盟文献共享服务平台- PHOSPHATASE

PHOSPHATASE: 作品数：255被引量：886H指数：14; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：储成才司丽珍曹守云于晓王洪梅更多>>; 相关机构：中国科学院遗传与发育生物学研究所山东大学湖北中医药大学安徽中医学院第一附属医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金瑞士科学基金更多>>

Tuning beneficial calcineurin phosphatase activation to counterα-synuclein toxicity in a yeast model of Parkinson’s disease: 《Neural Regeneration Research》2025年第1期199-200,共2页Srishti Chawla Mikael Molin Thomas Nystrom; Calcineurin(CN)is a calcium-and calmodulindependent serine/threonine that has been studied in many model organisms including yeast,filamentous fungi,plants,and mammals.Its biological functions range from ion homeostas...; 关键词：ACTIVATION DINUCLEAR CONSERVED

Overexpression of mitogen-activated protein kinase phosphatase-1 in endothelial cells reduces blood-brain barrier injury in a mouse model of ischemic stroke被引量：3: 《Neural Regeneration Research》2023年第8期1743-1749,共7页Xiu-De Qin Tai-Qin Yang Jing-Hui Zeng Hao-Bin Cai Shao-Hua Qi Jian-Jun Jiang Ying Cheng Long-Sheng Xu Fan Bu; supported by Research Start-up Funding of Shenzhen Traditional Chinese Medicine Hospital,No.2021-07(to FB);Sanming Project of Medicine in Shenzhen,No.SZZYSM 202111011(to XDQ and FB);Key Discipline Established by Zhejiang Province,Jiaxing City Jointly-Pain Medicine,No.2019-ss-ttyx(to LSX);Jiaxing Key Laboratory of Neurology and Pain Medicine,No.[2014]81(to LSX)。; Ischemic stroke can cause blood-brain barrier(BBB)injury,which worsens brain damage induced by stroke.Abnormal expression of tight junction proteins in endothelial cells(ECs)can increase intracellular space and BBB le...; 关键词：blood-brain barrier brain injury cerebral ischemia endothelial cells extracellular signal-regulated kinase 1/2 functional recovery mitogenactivated protein kinase phosphatase 1 OCCLUDIN oxygen and glucose deprivation transient middle cerebral artery occlusion

PTEN inhibitor bisperoxovanadium protects against noise-induced hearing loss被引量：1: 《Neural Regeneration Research》2023年第7期1601-1606,共6页Bei Fan Fei Lu Wei-Jia Du Jun Chen Xiao-Gang An Ren-Feng Wang Wei Li Yong-Li Song Ding-Jun Zha Fu-Quan Chen; supported by the National Natural Science Foundation of China,Nos.81670925(to FQC),81870732(to DJZ),81800918(to WL),81900933(to YLS);Department of Science and Technology Key Industry Innovation Chain Social Development Field Fund of Shaanxi Province,No.2021ZDLSF02-12(to FQC);the Natural Science Foundation of Shaanxi Province,No.2019JM-009(to JC).; Studies have shown that phosphatase and tensin homolog deleted on chromosome ten(PTEN)participates in the regulation of cochlear hair cell survival.Bisperoxovanadium protects against neurodegeneration by inhibiting PT...; 关键词：acoustic trauma Akt oxidative stress bisperoxovanadium cochlear hair cells loss inner hair cell ribbons loss noise exposure permanent threshold shift phosphatase and tensin homologue deleted on chromosome ten phosphatidylinositol 3 kinase siPTEN

Inhibiting phosphatase and actin regulator 1 expression is neuroprotective in the context of traumatic brain injury被引量：2: 《Neural Regeneration Research》2023年第7期1578-1583,共6页Yao Jing Lin Zhang Shi-Wen Chen Yan Guo Shi-Ming Ju Fang Yuan Hao Chen Dian-Xu Yang Heng-Li Tian Zhi-Ming Xu Jun Ding; supported by the National Natural Science Foundation of China,Nos.81501048(to JD),81801236(to ZMX),81974189(to HLT);Shanghai 6th People’s Hospital Research Fund,No.ynlc201808(to JD).; Studies have found that the phosphatase actin regulatory factor 1 expression can be related to stroke,but it remains unclear whether changes in phosphatase actin regulatory factor 1 expression also play a role in trau...; 关键词：apoptosis aquaporin 4 blood brain barrier intercellular adhesion molecule 1 NEUROINFLAMMATION nuclear factor kappa B OCCLUDIN phosphatase and actin regulator-1 traumatic brain injury zonula occludens 1

Axon regeneration induced by environmental enrichment-epigenetic mechanisms被引量：1: 《Neural Regeneration Research》2020年第1期10-15,共6页Bor Luen Tang; supported by the National University of Singapore Graduate School for Integrative Sciences and Engineering(to BLT); Environmental enrichment is known to be beneficial for cognitive improvement.In many animal models of neurological disorders and brain injury,EE has also demonstrated neuroprotective benefits in neurodegenerative dise...; 关键词：AXON regeneration CREB-binding protein DNA methylation/demethylation dorsal root GANGLION DRG neurons environmental enrichment epigenetics histone acetylation mechanistic target of rapamycin mTOR PHOSPHATASE and TENSIN HOMOLOGUE PTEN

Effects of microtubule-associated protein tau expression on neural stem cell migration after spinal cord injury被引量：6: 《Neural Regeneration Research》2016年第2期332-337,共6页Zhi-ping Qi Guo-xiang Wang Peng Xia Ting-ting Hou Hong-li Zhou Tie-jun Wang Xiao-yu Yang; supported by the National Natural Science Foundation of China,No.81250016,31572217; Our preliminary proteomics analysis suggested that expression of microtubule-associated protein tau is elevated in the spinal cord after injury. Therefore, the first aim of the present study was to examine tau express...; 关键词：nerve regeneration spinal cord injury tau protein neural stem cells transwelI chambers phosphatase 2A cell transplantation PHOSPHORYLATION MIGRATION okadaic acid C2-ceramide neural regeneration

Chronic neuroprotective effects of low concentration lithium on SH-SY5Y cells:possible involvement of stress proteins and gene expression被引量：1: 《Neural Regeneration Research》2014年第7期735-740,共6页Riadh Nciri Ezzeddine Bourogaa Samira Jbahi Mohamed Salah Allagui Abdelfattah Elfeki Christian Vincent Franoise Croute; To investigate the molecular mechanism underlying the neuroprotective effect of lithium on cells, in this study, we exposed SH-SY5Y cells to 0.5 mmol/L lithium carbonate （Li2CO2） for 25-50 weeks and then detected th...; 关键词：LITHIUM NEUROPROTECTION KINASE PHOSPHATASE stress proteins SH-SY5Y cells GENEEXPRESSION mechanism of action

What is the new target inhibiting the progression of Alzheimer's disease?: 《Neural Regeneration Research》2013年第21期1938-1947,共10页Lin Zhang Jing Yang Yunpeng Cao; To stop the progression of Alzheimer＇s disease in the early stage, it is necessary to identify new therapeutic targets. We examined striatal-enriched phosphatase 61 expression in the brain tissues of 12-month-old APP...; 关键词：neural regeneration brain injury NEURODEGENERATION Alzheimer’s disease striatal-enriched phosphatase 61 amyloid-beta peptide N-methyl-D-aspartate receptor GluN2B RNA interference immunohistochemistry western blot NEUROREGENERATION

Rapid construction of phosphatase and tensin homolog-deleted on chromosome ten gene recombinant adenovirus using the AdEasy system: 《Neural Regeneration Research》2010年第15期1166-1170,共5页Yongqiong Wei Lixue Chen Zhaofang Zeng Chongbiao Shen; Recent studies have shown that phosphatase and tensin homolog-deleted on chromosome ten （PTEN） gene plays an important role in ischemic brain damage and synaptic plasticity. The AdEasy system, which has been widely ...; 关键词：phosphatase and tensin homolog-deleted on chromosome ten recombinant adenovirus AdEasy system vector construction nerve factors neural regeneration

Nerve growth factor pretreatment against glutamate-induced hippocampal neuronal injury Action mechanism of phosphatase and tensin homologue deleted on chromosome 10被引量：12: 《Neural Regeneration Research》2010年第1期5-9,共5页Yae Hu Jiahui Mao Yan Zhu Ailing Zhou; the Natural Science Foundation of Jiangsu Province, No. BK2004048;the Social Development and Technology Plan of Nantong City, No. K2008009; BACKGROUND： Nerve growth factor （NGF） attenuates glutamate-induced injury to hippocampal neurons, and the human tumor suppressor gene phosphatase and tensin homologue deleted on chromosome 10 （PTEN） promotes neur...; 关键词：nerve growth factor GLUTAMATE phosphatase and tensin homologue deleted on chromosome 10 hippocampus neurons nerve factor

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