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作品数:630被引量:240H指数:8
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Predictive value of tacrolimus concentration/dose ratio in first posttransplant week for CYP3A5-polymorphism in kidney-transplant recipients
《World Journal of Transplantation》2025年第2期197-204,共8页Pham-Thai Dung Hoang-Xuan Su Nguyen-Chi Tue Nguyen-Huu Ben Nguyen-Minh Phuong Tuan-Ngoc Tran Phan-Ba Nghia Diem-Thi Van Nguyen Thi-Thuy Dung Hoang-Trung Vinh Lionel Rostaing Pham-Quoc Toan 
Supported by the Vietnam National Foundation for Science and Technology Development,No.NAFOSTED 04/2020/TN.
BACKGROUND Tacrolimus(TAC)is metabolized primarily by the CYP3A-encoded enzyme family(CYP3A4,CYP3A5,and CYP3A7).Individuals expressing the CYP3A51 allele are considered fast metabolizers and generally require higher T...
关键词:TACROLIMUS CYP3A5 Renal transplant recipient Concentration-to-dose Kidney transplant 
Independent risk factors for twin pregnancy adverse fetal outcomes before 28 gestational week by first trimester ultrasound screening
《World Journal of Radiology》2025年第1期41-48,共8页Hui-Ping Zhang Li Bao Jing-Jing Wu Yu-Qing Zhou 
Supported by Natural Science Foundation of Shanghai,China,No.22ZR1458200;Medical Ph.D Innovative Talent Base Project of Changning District,Shanghai,China,No.RCJD2021B09;Key Specialty of Changning District,Shanghai,China,No.20231004.
BACKGROUND The incidence of multiple pregnancies has increased worldwide recently and women with a twin pregnancy are at higher risk of adverse outcomes compared with women with a singleton pregnancy.It is important t...
关键词:Twin pregnancy First trimester ultrasound screening Uterine artery Pulsatility index Monochorionic diamniotic twin 
Influence of Infections on the 36-Week Survival of Chronic Hemodialysis Patients at the Hemodialysis Unit of the General Hospital of Douala, Cameroon
《Open Journal of Nephrology》2024年第4期593-608,共16页Elimby Ngande Lionel Patrick Joel Nguea Ndjame Arlette Fouda Menye Epouse Ebana Hermine Danielle 
Background: The absence of local data on the survival of hemodialysis patients complicates the optimization of their care in Cameroon, a country characterized by a high prevalence of chronic kidney disease (CKD). This...
关键词:SURVIVAL CKD HEMODIALYSIS Kaplan-Meier Estimator Cox Model 
基于单元主题的读写结合教学实践——以My week教学为例
《河北教育(教学版)》2024年第12期33-36,共4页毛丽伟 
《义务教育英语课程标准(2022年版)》课程实施部分给出明确教学建议:加强单元教学的整体性,推动实施单元整体教学。教师要强化素养立意,围绕单元主题,充分挖掘育人价值;要建立单元内各语篇内容之间及语篇育人功能之间的联系,形成具有整...
关键词:单元主题 学生核心素养 课程实施 单元整体教学 英语课程标准 主题意义 义务教育 育人价值 
Moxibustion versus non-moxibustion for immune reconstitution inflammatory syndrome in patients with HIV:A 48-week prospective cohort study
《World Journal of Acupuncture-Moxibustion》2024年第4期318-324,共7页Guo-jian GAO Hui-jun GUO Xin LI Yao-kai CHEN Xing-hua TAN Yu-qi YANG Jian-ping MA Shui-qing LIU Quan-sheng FENG Wen ZOU Ji-peng DONG Jian WANG Ying LIU 
Supported by National Major Science and Technology Projects:2017zX10205501;National Public Welfare Industry Scientific Research Special:201507005;2023 Beijing TCM Science and Technology Development Fund Project-Youth Project:BjzYQN-2023-05;China Academy of Chinese Medical Sciences Outstanding Youth Program:ZZ15-YQ-048.
Objective:To assess the effects of moxibustion on immune reconstitution inflammatory syndrome(IRIS)in patients with acquired immune deficiency syndrome(AIDS)by tracking T-cell subsets over a 48-week prospective cohort...
关键词:Acquired immune deficiency syndrome MOXIBUSTION Antiretroviral therapy T cell subset 
Long-term efficacy and safety of tenofovir alafenamide,tenofovir disoproxil fumarate,and entecavir in treating hepatitis B virus-related acute-on-chronic liver failure:A 144-week data analysis
《Liver Research》2024年第4期295-303,共9页Yeqiong Zhang Wenxiong Xu Zhexuan Deng Lu Wang Xingrong Zheng Xiang Zhu Xuejun Li Jianguo Li Xin Shu Jing Lai Liang Peng Chan Xie 
supported by grants from Key-Area Research and Development Program of Guangdong Province(No.2020B0101130015);Guangdong Medical Science and Technology Research Fund(No.A2021304);the Natural Science Foundation of China(No.82070611);Guangzhou Science and Technology Plan Projects(No.2023B03J1287);Guangzhou Science and Technology Program Key Projects(No.2023B01J1007);Sun Yat-Sen University Clinical Research 5010 Program(No.2020007);the Five-Year Plan of Third Affiliated Hospital of Sun Yat-sen University(No.2023W106);Clinical trial number:ClinicalTrials.gov ID:NCT03920618.
Background and aims:Antiviral therapy is essential for hepatitis B virus-related acute-on-chronic liver failure(HBV-ACLF).No data are available on the long-term prognosis or safety of tenofovir alafenamide(TAF),tenofo...
关键词:Tenofovir alafenamide(TAF) Tenofovir disoproxil fumarate(TDF) Entecavir(ETV) Hepatitis B virus(HBV) Acute-on-chronic liver failure(ACLF) 
Effect of three-week exercise program on muscle strength and joint mobility in patients with diabetic polyneuropathy:Randomized controlled trial
《World Journal of Diabetes》2024年第12期2311-2321,共11页Snježana Novaković-Bursać Goran Talić Nataša Tomić RankoŠkrbić Ivan Soldatovic 
BACKGROUND Limited joint mobility is the proven risk factor for diabetic foot ulceration when present in the subtalar and first metatarsophalangeal joints.Evidence shows that a foot-related exercise program,combined w...
关键词:DIABETES Diabetic polyneuropathy Diabetic foot ulcer Muscle strength Range of motion EXERCISE 
Anti-hepatitis B Virus Treatment with Tenofovir Amibufenamide Has No Impact on Blood Lipids: A Real-world, Prospective, 48-week Follow-up Study
《Journal of Clinical and Translational Hepatology》2024年第12期997-1008,共12页Yue Chen Wenkang Gao Huikuan Chu Afnan Ahmed Mohamed Al-Asbahi Shengqi Yan Hang Yuan Jiake Che Zilu Cheng Zexuan Li Jin Ye Rong Lin Xiaohua Hou Fan Du Ling Yang 
funded by the National Natural Science Foundation of China[82270614,81974078,81570530,and 81370550 to LY,82000561to HC];the National Key R&D Program of China[2023YFC2413804 to LY and 2022YFA1305600 to HC];the Science Foundation of Hubei Province[2019ACA133 to LY]and the Science Foundation of Union Hospital[2021xhyn005]to HC.
Background and Aims:The effect of tenofovir amibufenamide(TMF)on blood lipid profiles in patients with chronic hepatitis B(CHB)remains unclear.This study aimed to explore whether TMF affects blood lipids during 48 wee...
关键词:Tenofovir amibufenamide Antiviral treatment Chronic hepatitis B Blood lipid Virological response Palmitic acid 
以问题化学习推进语篇整体教学——PEP《英语》五年级上册Unit 2 My week Part C Story time磨课历程
《教学月刊(小学版)(综合)》2024年第11期8-12,共5页秦菊 
语篇整体教学是英语教学的重要组成部分,有助于学生构建完整的知识体系和学习框架。运用问题化学习理论指导语篇整体教学,能够帮助学生厘清知识脉络和结构,发展高阶思维,使知识真正转化为素养。以PEP《英语》五年级上册Unit 2 My week P...
关键词:问题化学习 语篇整体教学 磨课 
Who can benefit more from its twelve-week treatment:A prospective cohort study of blonanserin for patients with schizophrenia
《World Journal of Psychiatry》2024年第11期1735-1745,共11页Bao-Yan Xu Kun Jin Hai-Shan Wu Xue-Jun Liu Xi-Jin Wang Hong Sang Ke-Qing Li Mei-Juan Sun Hua-Qing Meng Huai-Li Deng Zhi-Yuan Xun Xiao-Dong Yang Lin Zhang Guan-Jun Li Rui-Ling Zhang Duan-Fang Cai Jia-Hong Liu Gui-Jun Zhao Long-Fa Liu Gang Wang Chang-Lie Zhao Bin Guo Sheng-Chun Jin Ling-Yun Huang Fu-De Yang Jian-Min Zheng Gui-Lai Zhan Mao-Sheng Fang Xiang-Jun Meng Guang-Ya Zhang Hai-Min Li Xiang-Lai Liu Ju-Hong Li Bin Wu Hai-Yun Li Jin-Dong Chen 
BACKGROUND Blonanserin(BNS)is a well-tolerated and effective drug for treating schizophrenia.AIM To investigate which types of patients would obtain the most benefit from BNS treatment.METHODS A total of 3306 particip...
关键词:SCHIZOPHRENIA BLONANSERIN EFFECTIVENESS Psychosocial functioning Prospective cohort study 
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