BRAIN-DERIVED

作品数:73被引量:370H指数:11
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  • 期刊=Neural Regeneration Researchx
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Brain-derived cell-free DNA被引量:1
《Neural Regeneration Research》2022年第10期2213-2214,共2页Dean Southwood Sanyukta Singh Zac Chatterton 
funded by The University of Sydney Postdoctoral Fellowship;funded by a National Health and Medical Research Council(NHMRC)-European Union Joint Program on Neurodegenerative Disease Research Grant(JPND2019-466-261&APP11912407).
Following cell death,DNA can be released into the blood plasma and other body fluids in the form of cell-free DNA(cfDNA).These DNA fragments are typically~167 bp in length,corresponding to the length of DNA wrapped ar...
关键词:FETAL MOTHER ENDOGENOUS 
The role of the TrkB-T1 receptor in the neurotrophin-4/5 antagonism of brain-derived neurotrophic factor on corticostriatal synaptic transmission被引量:2
《Neural Regeneration Research》2020年第11期1973-1976,共4页Elizabeth Hernandez-Echeagaray 
supported by Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica Grants No.216515 and IN 211718。
This manuscript reviews the function and fundamental characteristics of the neurotrophins and their receptors to introduce the reader to the differential effects exhibited by the neurotrophins;brain-derived neurotroph...
关键词:BRAIN-DERIVED NEUROTROPHIC factor NEUROTROPHIN 4/5 occlusive striatum synergic TrkB-FL TrkB-T1 
The role of exercise in brain DNA damage被引量:1
《Neural Regeneration Research》2020年第11期1981-1985,共5页Thais Cereser Vilela Vanessa Moraes de Andrade Zsolt Radak Ricardo Aurino de Pinho 
Cells are constantly subjected to cytotoxic and genotoxic insults resulting in the accumulation of unrepaired damaged DNA,which leads to neuronal death.In this way,DNA damage has been implicated in the pathogenesis of...
关键词:aerobic EXERCISE apoptosis BRAIN-DERIVED NEUROTROPHIC factor BRAIN DNA damage DNA repair NEURODEGENERATIVE disease oxidative stress physical EXERCISE strength EXERCISE 
Paired associated magnetic stimulation promotes neural repair in the rat middle cerebral artery occlusion model of stroke被引量:8
《Neural Regeneration Research》2020年第11期2047-2056,共10页Bei-Yao Gao Cheng-Cheng Sun Guo-Hua Xia Shao-Ting Zhou Ye Zhang Ye-Ran Mao Pei-Le Liu Ya Zheng Dan Zhao Xu-Tong Li Janie Xu Dong-Sheng Xu Yu-Long Bai 
supported by the National Natural Science Foundation of China,Nos.81974358,81772453(to DSX)。
Paired associative stimulation has been used in stroke patients as an innovative recovery treatment.However,the mechanisms underlying the therapeutic effectiveness of paired associative stimulation on neurological fun...
关键词:BRAIN-DERIVED NEUROTROPHIC factor finite element simulation glutamate receptor IPSILATERAL hemisphere paired associative STIMULATION PSD95 resting-state functional MRI STROKE SYNAPSIN I transcranial magnetic STIMULATION 
Modified constraint-induced movement therapy alters synaptic plasticity of rat contralateral hippocampus following middle cerebral artery occlusion被引量:20
《Neural Regeneration Research》2020年第6期1045-1057,共13页Bei-Yao Gao Dong-Sheng Xu Pei-Le Liu Ce Li Liang Du Yan Hua Jian Hu Jia-Yun Hou Yu-Long Bai 
supported by the National Natural Science Foundation of China,No.81871841(to YLB) and No.81772453(to DSX)
Modified constraint-induced movement therapy is an effective treatment for neurological and motor impairments in patients with stroke by increasing the use of their affected limb and limiting the contralateral limb.Ho...
关键词:BRAIN-DERIVED NEUROTROPHIC factor glutamate HIPPOCAMPUS m CIMT middle cerebral artery occlusion MODIFIED constraint-induced movement therapy α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor 
Proprotein convertase 1/3-mediated down-regulation of brain-derived neurotrophic factor in cortical neurons induced by oxygen-glucose deprivation被引量:3
《Neural Regeneration Research》2020年第6期1066-1070,共5页Xiang-Yang Zhang Feng Liu Yan Chen Wei-Chun Guo Zhao-Hui Zhang 
supported by the National Nature Science Foundation of China,No.81501053(to YC)
Brain-derived neurotrophic factor(BDNF)has robust effects on synaptogenesis,neuronal differentiation and synaptic transmission and plasticity.The maturation of BDNF is a complex process.Proprotein convertase 1/3(PC1/3...
关键词:cortical neuron ischemia NEUROTROPHIN oxygen-glucose deprivation precursor protein of BRAIN-DERIVED NEUROTROPHIC factor PROPROTEIN CONVERTASE PROPROTEIN CONVERTASE 1/3 
Identification of protein targets for the antidepressant effects of Kai-Xin-San in Chinese medicine using isobaric tags for relative and absolute quantitation被引量:4
《Neural Regeneration Research》2020年第2期302-310,共9页Xian-Zhe Dong Dong-Xiao Wang Tian-Yi Zhang Xu Liu Ping Liu Yuan Hu 
supported by the National Natural Science Foundation of China,No.81573876(to YH)
Kai-Xin-San consists of Ginseng Radix, Polygalae Radix, Acori Tatarinowii Rhizoma, and Poria at a ratio of 3:3:2:2. Kai-Xin-San has been widely used for the treatment of emotional disorders in China. However, no studi...
关键词:BRAIN-DERIVED neurotrophic factor signal pathway depression ISOBARIC tags for RELATIVE and absolute quantitation Kai-Xin-San neurogenesis protein network proteomics analysis synaptic plasticity traditional Chinese medicine 
Adipose-derived stem cells modified by BDNF gene rescue erectile dysfunction after cavernous nerve injury被引量:6
《Neural Regeneration Research》2020年第1期120-127,共8页Mei Yang Jiang-Yang Sun Cheng-Cheng Ying Yong Wang Yong-Lian Guo 
supported by the Natural Science Foundation of Hubei Province of China,No.2017CFB176(to CCY);the Fundamental Research Funds for The Central Hospital of Wuhan of China,No.YB16A01(to CCY)
Cavernous nerve injury is the main cause of erectile dysfunction following radical prostatectomy.The recovery of erectile function following radical prostatectomy remains challenging.Our previous studies found that in...
关键词:adipose-derived stem cells BRAIN-DERIVED NEUROTROPHIC factor CAVERNOUS nerve injury erectile dysfunction infection intracavernous injection LENTIVIRAL vector neuronal NITRIC oxide synthase radical prostatectomy 
Hyodeoxycholic acid protects the neurovascular unit against oxygen-glucose deprivation and reoxygenation-induced injury in vitro被引量:16
《Neural Regeneration Research》2019年第11期1941-1949,共9页Chang-Xiang Li Xue-Qian Wang Fa-Feng Cheng Xin Yan Juan Luo Qing-Guo Wang 
supported by the National Natural Science Foundation of China,No.81430102(to QGW)
Calculus bovis is commonly used for the treatment of stroke in traditional Chinese medicine. Hyodeoxycholic acid(HDCA) is a bioactive compound extracted from calculus bovis. When combined with cholic acid, baicalin an...
关键词:hyodeoxycholic acid oxygen glucose deprivation and REOXYGENATION blood-brain barrier permeability anti-oxidative anti-inflammatory ANTI-APOPTOTIC BRAIN-DERIVED NEUROTROPHIC FACTOR glial cell line-derived NEUROTROPHIC FACTOR ischemic stroke in vitro NEUROVASCULAR unit 
Paired associative stimulation improves synaptic plasticity and functional outcomes after cerebral ischemia被引量:6
《Neural Regeneration Research》2019年第11期1968-1976,共9页Yan Hu Tie-Cheng Guo Xiang-Yu Zhang Jun Tian Yin-Shan Lu 
supported by the National Natural Science Foundation of China,No.81272156(to TCG)
Paired associative stimulation is a relatively new non-invasive brain stimulation technique that combines transcranial magnetic stimulation and peripheral nerve stimulation. The effects of paired associative stimulati...
关键词:cerebral ischemia paired associative stimulation cognitive function long-term POTENTIATION SYNAPTIC plasticity MORRIS water maze SYNAPTIC structure N-methyl-D-aspartic acid receptor BRAIN-DERIVED NEUROTROPHIC factor MULTI-ELECTRODE array neural regeneration 
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