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DEGENERATION: 作品数：521被引量：1030H指数：13; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：施杞梁倩倩王拥军侯炜崔学军更多>>; 相关机构：上海中医药大学复旦大学青岛大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划中国博士后科学基金更多>>

Inhibition of the NLRP3 inflammasome attenuates spiral ganglion neuron degeneration in aminoglycoside-induced hearing loss被引量：1: 《Neural Regeneration Research》2025年第10期3025-3039,共15页Jia Fang Zhuangzhuang Li Pengjun Wang Xiaoxu Zhang Song Mao Yini Li Dongzhen Yu Xiaoyan Li Yazhi Xing Haibo Shi Shankai Yin; supported by the National Natural Science Foundation of China,Nos.81800919(to YX),82171140(to PW);the International Cooperation and Exchange of the National Natural Science Foundation of China,Nos.82020108008(to HS),81720108010(to SY).; Aminoglycosides are a widely used class of antibacterials renowned for their effectiveness and broad antimicrobial spectrum.However,their use leads to irreversible hearing damage by causing apoptosis of hair cells as ...; 关键词：DEGENERATION hearing loss macrophages Mcc950 neuroinflammation NLRP3 inflammasome OTOTOXICITY pyroptosis sensorineural hearing loss spiral ganglion neuron

Mechanisms behind elevated serum levels of plasminogen activator inhibitor-1 in frontotemporal lobar degeneration: 《Neural Regeneration Research》2025年第8期2317-2318,共2页Francesco Angelucci Jakub Hort; funded by the project National Institute for Neurological Research(Programme EXCELES,ID Project No.LX22NPO5107);TEAMING:857560(EU);CZ.02.1.01/0.0/0.0/17_043/0009632(CZ)(to FA and JH)。; Frontotemporal lobar degeneration(FTLD)is a form of progressive dementia characterized by degeneration of the frontal and temporal lobes of the brain.This pathology involves a series of cognitive,behavioral,and neurol...; 关键词：DEGENERATION ELEVATED PATHOLOGY

Role of glutathione transferase in phase separation of FUS and TAF15 in neurons: 《Neural Regeneration Research》2025年第7期1999-2000,共2页Kiyoung Kim; supported by the BK21 FOUR(Fostering Outstanding Universities for Research)and the Basic Science Research Program through the National Research Foundation of Korea(NRF),funded by the Ministry of Education(MOE)and the Ministry of Science and ICT(MSIT)(NRF-2022R1A2C1004204,RS-2023-00219563,2023-DD-UP-0007);by the Soonchunhyang University Research Fund(to KK)。; Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord,leading to muscle weakness,paralysis,and ultimately death(C...; 关键词：DEGENERATION FUS AGGREGATION

Dendritic spine degeneration:a primary mechanism in the aging process: 《Neural Regeneration Research》2025年第6期1696-1698,共3页Gonzalo Flores Leonardo Aguilar-Hernández Fernado García-Dolores Humberto Nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán; funded by CONAHCYT grant(252808)to GF;CONAHCYT’s“Estancias Posdoctorales por México”program(662350)to HTB。; Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a w...; 关键词：AGING PROCESS STRESS

Targeting cholesterol trafficking to mitigate axonal degeneration in hereditary spastic paraplegia: 《Neural Regeneration Research》2025年第5期1397-1398,共2页Zhenyu Chen Xue-Jun Li; supported by the NIH grant(RO1 NS118066);the Blazer Foundation(to XJL)。; Axonal degeneration underlies many debilitating diseases including hereditary spastic paraplegia(HSP),a genetically and clinically diverse group of disorders characterized by spasticity and weakness of the lower extre...; 关键词：DEGENERATION DISEASES HEREDITARY

Monogenic gene therapy for glaucoma and optic nerve injury: 《Neural Regeneration Research》2025年第3期815-816,共2页Chikako Harada Xiaoli Guo Takayuki Harada; supported by Japan Society for the Promotion of Science (JSPS) KAKENHI Grants-in-Aid for Scientific Research (JP22K09804 to CH;JP21K09688 to XG;JP19KK0229, JP21H04786, JP21H02819 and JP21K18279 to TH);the Shiseido Female Researcher Science Grant (to XG);Mitsubishi Foundation;Takeda Science Foundation (to TH)。; The prevalence of glaucoma, the second leading cause of global blindness, is increasing due to aging populations. In glaucoma, degeneration of the optic nerve and retinal ganglion cells(RGCs) causes visual field defec...; 关键词：VISUAL GLAUCOMA DEGENERATION

Calcium channels caught in peripheral glia’s tug-of-war on axon regeneration in Drosophila: 《Neural Regeneration Research》2025年第2期475-476,共2页Jackson Powell Tobias Steinschaden Rose Horowitz Yuanquan Song; Neural damage or degeneration is at the crux of many diseases,and treatment of these diseases will require the development of therapeutics to enhance and guide neural regeneration.Both intrinsic and extrinsic factors ...; 关键词：DEGENERATION FIRING SYSTEM

A-kinase anchoring protein-mediated compartmentalization of pro-survival signaling in the retina: 《Neural Regeneration Research》2025年第2期479-480,共2页Joanna Mackiewicz Tomasz Boczek; supported by National Science Center(Narodowe Centrum Nauki)grant No.UMO-2019/33/B/NZ4/00587 to TB.; The retina plays a fundamental role in the process of vision,serving as the primary interface between external visual stimuli and the central nervous system.Because the retina is exposed to a variety of environmental ...; 关键词：DEGENERATION utilizing IRREVERSIBLE

Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury: 《Neural Regeneration Research》2025年第2期587-597,共11页Tong Li Hui-Min Xing Hai-Dong Qian Qiao Gao Sheng-Lan Xu Hua Ma Zai-Long Chi; supported by the National Natural Science Foundation of China,No.82271114;the Natural Science Foundation of Zhejiang Province of China,No.LZ22H120001(both to ZLC).; Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured neurons.However,a poor integration rate and high risk of tumorigenicity after cell transplantation limit...; 关键词：EXOSOME miRNA neural progenitor cell NEURODEGENERATION NEUROINFLAMMATION neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

Glial response in the midcingulate cortex in Huntington’s disease: 《Neural Regeneration Research》2025年第1期207-208,共2页Thulani H.Palpagama Andrea Kwakowsky; Huntington’s disease(HD)is a genetic disease characterized by the progressive degeneration of the striatum and cortex.Patients can present with a variety of symptoms that can broadly be classified into motor symptoms...; 关键词：HUNTINGTON DEGENERATION CORTEX

DEGENERATION