supported by the Beijing Natural Science Foundation(Grant No.2123062);Research Fund for the Doctoral Program of Higher Education of China(Grant No.20121103120008);Science and Tech-nology Foundation of Beijing University of Technology(Grant No.ykj-2012-8725)
The c-Jun N-terminal kinase (JNK) is involved in a variety of important cellular processes and aberrant JNK activity is associated with many human diseases.The ligand-based and receptor-based alignment rules were us...