UPREGULATION

作品数：256被引量：1123H指数：17
导出分析报告
相关领域：医药卫生生物学更多>>
相关作者：刘晓光张光先钱俊良朱华宇徐广银更多>>
相关机构：中山大学天津医科大学第二军医大学第四军医大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Exosomes originating from neural stem cells undergoing necroptosis participate in cellular communication by inducing TSC2 upregulation of recipient cells following spinal cord injury
《Neural Regeneration Research》2025年第11期3273-3286,共14页Shiming Li Jianfeng Li Guoliang Chen Tao Lin Penghui Zhang Kuileung Tong Ningning Chen Shaoyu Liu 
supported by the National Natural Science Foundation of China,No.81801907(to NC);Shenzhen Key Laboratory of Bone Tissue Repair and Translational Research,No.ZDSYS20230626091402006(to NC);Sanming Project of Medicine in Shenzhen,No.SZSM201911002(to SL);Foundation of Shenzhen Committee for Science and Technology Innovation,Nos.JCYJ20230807110310021(to NC),JCYJ20230807110259002(to JL);Science and Technology Program of Guangzhou,No.2024A04J4716(to TL)。
We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord injury.While exosomes are recognized as playing a pivotal role in neural stem cells exocrine func...
关键词：cellular communication competing endogenous RNA EXOSOMES Foxp1 NECROPTOSIS neural stem cells Slc16a3 spinal cord injury transcriptome sequencing Tsc2 
Induced neural stem cells regulate microglial activation through Akt-mediated upregulation of CXCR4 and Crry in a mouse model of closed head injury
《Neural Regeneration Research》2025年第5期1416-1430,共15页Mou Gao Qin Dong Dan Zou Zhijun Yang Lili Guo Ruxiang Xu 
supported by the National Natural Science Foundation of China,Nos.82271397(to MG),82001293(to MG),82171355(to RX),81971295(to RX),and 81671189(to RX)。
Microglial activation that occurs rapidly after closed head injury may play important and complex roles in neuroinflammation-associated neuronal damage and repair.We previously reported that induced neural stem cells ...
关键词：Akt signaling cerebral edema closed head injury Crry CXCR4 induced neural stem cell MICROGLIA NEUROINFLAMMATION 
Plantamajoside mitigates endoplasmic reticulum stress-mediated pancreatic β-cell apoptosis in type 2 diabetes via DNAJC1 upregulation
《World Journal of Diabetes》2025年第4期318-325,共8页Md Abdul Alim Al-Bari Fabian Davamani Payal Bhatnagar Nabil Eid 
Diabetes mellitus(DM)is a metabolic disorder characterized by persistent hyperglycemia and other symptoms,which pose significant challenges to individual health,life expectancy,and public healthcare systems.The escala...
关键词：Plantamajoside Type 2 diabetes mellitus PI3K/AKT/NF-κB pathway Endoplasmic stress METFORMIN DNAJC1 Apoptosis AUTOPHAGY 
Arecoline,a main alkaloid in Areca catechu,induces biological changes in human papillomavirus 16-positive cervical cancer cells via upregulation of viral oncogenes and cellular transcriptional factors
《Asian Pacific Journal of Tropical Biomedicine》2025年第3期119-128,I0016-I0018,共13页Jureeporn Chuerduangphui Chaleampol Loymunkong Tipaya Ekalaksananan Chamsai Pientong 
Objective:To investigate the effects of arecoline on HPV-positive cervical cells and unveil its underlying mechanism in cervical carcinogenesis.Methods:The cytotoxicity of arecoline was determined and the effect of su...
关键词：ARECOLINE Human papillomavirus ONCOGENES Cervical cancer c-Fos 
Long noncoding RNA LINC01106 promotes lung adenocarcinoma progression via upregulation of autophagy
《Oncology Research》2025年第1期171-184,共14页GENGYUN SUN YIPING ZHENG JIANFENG CAI JIE GAO LIE DONG XIANGBIN ZHANG YINGHUI HUANG 
supported by the 2022 Natural Science Foundation of Fujian Province(No.2022J011486).
Background:Long noncoding RNA,LINC01106 exhibits high expression in lung adenocarcinoma(LUAD)tumor tissues,but its functional role and regulatory mechanism in LUAD cells remain unclear.Methods:LINC01106 expression was...
关键词：LINC01106 TAF15 TEAD4 ATG5 Lung adenocarcinoma(LUAD) Non-small cell lung cancer(NSCLC) 
Stabilization of EREG via STT3B-mediated N-glycosylation is critical for PDL1 upregulation and immune evasion in head and neck squamous cell carcinoma
《International Journal of Oral Science》2024年第4期728-742,共15页Shengming Xu Haifeng Wang Yu Zhu Yong Han Liu Liu Xiangkai Zhang Jingzhou Hu Wuchang Zhang Shengzhong Duan Jiong Deng Zhiyuan Zhang Shuli Liu 
supported by the Fundamental Research program funding of Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine(JYZZ233);the National Nature Science Foundation of China(grant numbers81802696,82172565);The CAMS Innovation Fund for Medical Sciences(CIFMS)(Project No.2019-I2M-5-037);Shanghai Clinical Research Center for Oral Diseases(19MC1910600)。
Dysregulated Epiregulin(EREG)can activate epidermal growth factor receptor(EGFR)and promote tumor progression in head and neck squamous cell carcinoma(HNSCC).However,the mechanisms underlying EREG dysregulation remain...
关键词：PDL1 SQUAMOUS inhibited 
Vanillylacetone attenuates cadmium chloride-induced hippocampal damage and memory loss through upregulation of nuclear factor erythroid 2-related factor 2 gene and protein expression
《Neural Regeneration Research》2024年第12期2750-2759,共10页Fahaid H.A.L-Hashem Salah O.Bashir Amal F.Dawood Moutasem S.Aboonq Ismaeel Bin-Jaliah Abdulaiziz M.Al-Garni Mohamed D.Morsy 
funded by the Research Deanship of King Khalid University,No.GRP-215-43 (to FHA);Princess Nourah bint Abdulrohman University Researchers Supporting Project,No.PNURSP2023R110 (to AFD)。
Memory loss and dementia are major public health concerns with a substantial economic burden.Oxidative stress has been shown to play a crucial role in the pathophysiology of hippocampal damage-induced memory impairmen...
关键词：HIPPOCAMPUS NEUROPROTECTIVE Nrf2 gene oxidative stress vanillylacetone 
Bioengineered silver nanoparticles induced apoptosis through upregulation of caspase 3 and caspase 8 proteins in breast adenocarcinoma MDA-MB-231 cells and impede angiogenesis
《Particuology》2024年第12期252-264,共13页Shahnaz Majeed Nurul Izzah Binti Abu Bakar Mohammad Danish Afzan Binti Mahmad Mohamad Nasir Mohamad Ibrahim Norul Aini Zakariya Sreenivas Patro Sisinthy Ravindran Muthukumarasamy Abdulaziz M.Alanazi Mohammed Tahir Ansari Ohoud A.Jefri 
In recent years,a lot of research has been done on silver nanoparticles(SNP)due to their numerous applications in the biomedical,pharmaceutical,and drug delivery industries.In this present study SNP were green synthes...
关键词：Silver nanoparticles TEM ANTI-ANGIOGENESIS DAPI ROS 
Small ubiquitin-like modifiers inhibitors lower blood pressure via ERK5/KLF2-dependent upregulation of the eNOS/NO pathway
《Frigid Zone Medicine》2024年第4期202-211,共10页Nannan Tang Jiatong Li Zhuo Wang Jinlu Zuo Zifeng Zhang Di Huang Yannan Han Yuqing Chen Yilin Sun Xiang Li Ruxue Mu Qingxue Ma Jie Zhang Jiaying Wu He Wang Hongxia Zhao Xingli Dong Zhiguo Wang Yu Liu Dan Zhao Baofeng Yang 
supported by the National Natural Science Foundation of China(82330011,U21A20339);the CAMS Innovation Fund for Medical Sciences(CIFMS,2020-I2M-5-003);the National Natural Science Foundation of China(No.82370302,31871175);Natural Science Foundation of Heilongjiang Province of China(No.YQ2019H003);College of Pharmacy,Harbin Medical University Excellent Young Talents Funding(No.2020-YQ-01).
Background:Small ubiquitin-like modifiers(SUMO)ylation is a dynamic and reversible post-translational modification playing pivotal roles in the regulation of cancer,diabetes,heart failure,and neurological diseases.How...
关键词：hypertension SUMO inhibitor ERK5 SUMOYLATION KLF2 
PRR34-AS1 promotes mitochondrial division and glycolytic reprogramming in hepatocellular carcinoma cells through upregulation of MIEF2
《Acta Biochimica et Biophysica Sinica》2024年第11期1604-1617,共14页Xuejing Yang Huijing Feng Jonghwa Kim Gang Ti Lin Wang Kun Wang Dong Song 
This work was supported by the grants from the Natural Science Research Project of Shanxi Basic Research Program(No.202203021221246);the Scientific Research Project of Shanxi Provincial Health Commission(No.2022009).
LncRNA PRR34-AS1 overexpression promotes the proliferation and invasion of hepatocellular carcinoma(HCC)cells,but whether it affects HCC energy metabolism remains unclear.Mitochondrial division and glycolytic reprogra...
关键词：glucose metabolism reprogramming hepatocellular carcinoma lncRNA PRR34-AS1 mitochondrial division PROLIFERATION 
全选清除导出
共26页<12345678910>
检索报告 对象比较 聚类工具 使用帮助 返回顶部