云南高校图书馆联盟文献共享服务平台- MACROAUTOPHAGY

MACROAUTOPHAGY: 作品数：19被引量：417H指数：7; 导出分析报告; 相关领域：生物学更多>>; 相关机构：东北林业大学更多>>; 相关期刊：《Cellular & Molecular Immunology》《Frontiers in Biology》《World Journal of Gastroenterology》《Genes & Diseases》更多>>; 相关基金：国家自然科学基金重庆市自然科学基金上海市自然科学基金上海市青年科技启明星计划更多>>

Beclin-1/LC3-II dependent macroautophagy was uninfluenced in ischemia-challenged vascular endothelial cells被引量：6: 《Genes & Diseases》2022年第2期549-561,共13页Yaping Ma Chaofan Li Yan He Tiwei Fu Li Song Qingsong Ye Fugui Zhang; This work was supported by the National Natural Science Foundation of China(No.81400493);Scientific and Technological Research Program of Chongqing Municipal Education Commission(No.KJQN20200429);Joint Medical Research Project by Chongqing Health Commission and Natural Science Foundation of Chongqing(No.2020GDRC008).; Autophagy has been extensively studied and occurs in many biological settings.However,a question remains as to whether ischemia enhances Beclin-1/LC3-II-dependent macroautophagy in vascular endothelial cells,as has be...; 关键词：AUTOPHAGY Bioinformatics analysis Human umbilical vein endothelial cell Quantitative proteomics study Skin flap

Autophagy-lysosome pathway as a source of candidate biomarkers for Parkinson's disease: 《Neuroimmunology and Neuroinflammation》2021年第2期101-110,共10页Nikolaos Papagiannakis Leonidas Stefanis; Parkinson's disease(PD)is a neurodegenerative disorder characterized by progressive motor disturbances and affects more than 1%of the worldwide population.Diagnosis of PD relies on clinical history and physical examin...; 关键词：MACROAUTOPHAGY chaperone-mediated autophagy SYNUCLEINOPATHY Lewy bodies Gaucher disease GLUCOCEREBROSIDASE Hsc70

Adaptive immunity at the crossroads of autophagy and metabolism被引量：3: 《Cellular & Molecular Immunology》2021年第5期1096-1105,共10页Shree Padma Metur Daniel J.Klionsky; The function of lymphocytes is dependent on their plasticity,particularly their adaptation to energy availability and environmental stress,and their protein synthesis machinery.Lymphocytes are constantly under metabol...; 关键词：IMMUNOLOGY LYSOSOME MACROAUTOPHAGY STRESS

Autophagy and inflammation in ischemic stroke被引量：110: 《Neural Regeneration Research》2020年第8期1388-1396,共9页Yun Mo Yin-Yi Sun Kang-Yong Liu; supported by the Natural Science Foundation of Shanghai of China,No.17ZR1425800(to KYL);the Shanghai Pudong District Health Bureau of China,No.PDZX2017-25(to KYL); Appropriate autophagy has protective effects on ischemic nerve tissue,while excessive autophagy may cause cell death.The inflammatory response plays an important role in the survival of nerve cells and the recovery of...; 关键词：AUTOPHAGY cerebral ischemia function INFLAMMASOME INFLAMMATION ischemia/refusion ischemic stroke MACROAUTOPHAGY NEUROINFLAMMATION oxygen glucose deprivation

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy被引量：13: 《Translational Neurodegeneration》2019年第1期215-229,共15页Jia-Zhen Wu Mustafa Ardah Caroline Haikal Alexander Svanbergsson Meike Diepenbroek Nishant N.Vaikath Wen Li Zhan-You Wang Tiago F.Outeiro Omar M.El-Agnaf Jia-Yi Li; We would like to acknowledge financial supports by the National Natural Science Foundation(81430025,81701265,31800898,U801681);Acknowledgements are also to the supports of the Swedish Research Council(K2015-61X-22297-03-4);EU-JPND(aSynProtec),EU-JPND(REfrAME),EU H2020-MSCA-ITN-2016(Syndegen),BAGADILICO-Excellence in Parkinson and Huntington Research,the Strong Research Environment MultiPark(Multidisciplinary research on Parkinson’s disease),the Swedish Parkinson Foundation(Parkinsonfonden),Torsten Söderbergs Foundation,Olle Engkvist Byggmästere Foundation;W.L.is supported by a scholarship from the China Scholarship Council;TFO is supported by the DFG Center for Nanoscaly Microscopy and Molecular Physiology of the Brain(CNMPB).; Background:Progressive accumulation ofα-synuclein is a key step in the pathological development of Parkinson’s disease.Impaired protein degradation and increased levels ofα-synuclein may trigger a pathological aggr...; 关键词：chaperone-mediated autophagy MACROAUTOPHAGY ALPHA-SYNUCLEIN protein aggregation Parkinson disease lysosomal-associated membrane protein

Increased Macroautophagy in Interferon-Gamma-Producing T Cells from Patients with Newly Diagnosed Systemic Lupus Erythematosus被引量：3: 《Chinese Medical Journal》2018年第13期1527-1532,共6页Xiong-Yan Luo Jia-Li Yuan Jing Liu Cai-Nan Luo Ming-Hui Yang Qin Wei Min Yang Yong Chen Yi Liu Guo-Hua Yuan; Background： Imbalance of interferon-gamma （IFN-γ）, interleukin （IL）-4, and IL-17 producing by T cells is confirmed to contribute to the pathogenesis of systemic lupus erythematosus （SLE）. Autophagy is now emer...; 关键词：AUTOPHAGY Lupus Erythematosus SYSTEMIC T Helper cells

Dysregulation of autophagy and mitochondrial function in Parkinson’s disease被引量：7: 《Translational Neurodegeneration》2016年第1期152-160,共9页Bao Wang Neeta Abraham Guodong Gao Qian Yang; The works were supported by National Natural Science Foundation of China(Grant No.31371400)(Q.Y)and(Grant No.31671060)(Q.Y).; Parkinson’s disease(PD)is the second most common neurodegenerative disease.Increasing evidence supports that dysregulation of autophagy and mitochondrial function are closely related with PD pathogenesis.In this revi...; 关键词：Parkinson’s disease AUTOPHAGY MACROAUTOPHAGY MITOPHAGY Chaperone-mediated autophagy Mitochondria α-synuclein PINK/Parkin LRRK2 DJ-1

Structural biology of the macroautophagy machinery被引量：1: 《Frontiers in Biology》2014年第1期18-34,共17页Leon H. CHEW Calvin K. YIP; Macroautophagy is a conserved degradative process mediated through formation of a unique double- membrane structure, the autophagosome. The discovery of autophagy-related （Atg） genes required for autophagosome forma...; 关键词：MACROAUTOPHAGY AUTOPHAGY Atg proteins structural biology X-ray crystallography single-particle electronmicroscopy

The machinery of macroautophagy被引量：177: 《Cell Research》2014年第1期24-41,共18页Yuchen Feng Ding He Zhiyuan Yao Daniel J Klionsky; Autophagy is a primarily degradative pathway that takes place in all eukaryotic cells. It is used for recycling cytoplasm to generate macromolecular building blocks and energy under stress conditions, to remove superf...; 关键词：AUTOPHAGOSOME AUTOPHAGY degradation LYSOSOME phagophore stress VACUOLE

Overview of macroautophagy regulation in mammalian cells被引量：70: 《Cell Research》2010年第7期748-762,共15页Maryam Mehrpour; Macroautophagy is a multistep, vacuolar, degradation pathway terminating in the lysosomal compartment, and it is of fundamental importance in tissue homeostasis. In this review, we consider macroautophagy in the light...; 关键词：AUTOPHAGY cell signaling intracellular trafficking LYSOSOMES PROTEOLYSIS

MACROAUTOPHAGY