云南高校图书馆联盟文献共享服务平台- DEGRANULATION

DEGRANULATION: 作品数：29被引量：34H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：梁玉婷李莉王磊吉晓滨臧林泉更多>>; 相关机构：上海市第一人民医院广州市第一人民医院中山大学广州医学院更多>>; 相关期刊：《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《Advances in Biological Chemistry》《Journal of Clinical & Translational Research》更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划中国博士后科学基金国家重点基础研究发展计划更多>>

Melatonergic Signaling Sustains Food Allergy Through FcεRI Recycling: 《Research》2025年第1期752-764,共13页Youxia Wang Xinmei Zhang Ifen Hung Chunxue Liu Wenkai Ren Liangpeng Ge Hao Wang; supported by the National Natural Science Foundation of China(U22A20510 and 32225047);Laboratory of Lingnan Modern Agriculture Project(NT2021005);Double first-class discipline promotion project(2023B10564001);National Center of Technology Innovation for Pigs(NCTIP-XD/B13).; The prevalence of food allergies is increasing dramatically and causing serious public health concerns.Notably,melatonin metabolism imbalance in patients with food allergies;however,the role of melatonin in food aller...; 关键词：food allergieshoweverthe degranulation mast cells reprograms gut microbiota gut microbiota food allergy aggravates food allergy suppresses food allergy MELATONIN

Targeted nuclear degranulation of neutrophils promotes the progression of pneumonia in ulcerative colitis: 《Precision Clinical Medicine》2024年第4期307-317,共11页Yiming Shao Qibing Zheng Xiaobei Zhang Ping Li Xingxin Gao Liming Zhang Jiahong Xu Lingchao Meng Yanyun Tian Qinqin Zhang Guangxi Zhou; supported by grants from the National Natural Science Foundation of China(Grants No.82270562,82302800);China Postdoctoral Science Foundation(Grant No.2024M751108);Tai Shan Young Scholar Foundation of Shandong Province(Grant No.tsqn202103190);Postdoctoral Fund of The Affiliated Hospital of Jining Medical University(Grant No.JYFY364862);Postdoctoral Innovation Program in Shandong Province(Grant No.SDCX-ZG-202400032);Doctor Fund of The Affiliated Hospital of Jining Medical University(Grant No.2022-BS-07)。; Background:Both intestinal and pulmonary systems are parts of the mucosal immune system,comprising~80%of all immune cells.These immune cells migrate or are transported between various mucosal tissues to maintain tissu...; 关键词：NEUTROPHILS targeted nuclear degranulation reverse migration ulcerative colitis PNEUMONIA

Eosinophil extracellular traps in respiratory ailment:Pathogenic mechanisms and clinical translation: 《World Journal of Otorhinolaryngology-Head and Neck Surgery》2024年第3期213-224,共12页Shun-Yu Wu Bo-Yu Cai Tian-Yu Wang Zhi-Wen Cao Hu Peng Huan-Hai Liu; Department of Otolaryngological,Shanghai Changzheng Hospital,Grant/Award Number:0907;National ScienceFoundationof China,Grant/Award Numbers:81541038,81670905,81870702。; Background:Eosinophilic extracellular traps(EETs)are reticular complexes comprising deoxyribonucleic-Acid(DNA)fibers and granule proteins.Aims:EETs play a crucial role in antimicrobial host responses and are pathogeni...; 关键词：CYTOLYSIS DEGRANULATION eosinophil extracellular traps eosinophils respiratory ailments

Guizhi-Shaoyao-Zhimu decoction attenuates rheumatoid arthritis by inhibiting mast cell degranulation: 《Traditional Medicine Research》2023年第6期39-48,共10页Lin Li Xiang-Yu Kong Wu Chen Mei-Jiao Wang Zhi-Xing He Yun Zhang Cheng-Ping Wen Qiao Wang Lin Huang; funded by Zhejiang Nature Science Foundation(LQ20H270006);National Key R&D Program of China(No.2018YFC1705500).; Background:In this study,we investigated whether prophylactic treatment with Guizhi-Shaoyao-Zhimu decoction(GSZ)could delay the onset of rheumatoid arthritis by targeting mast cells.Methods:Collagen-induced arthritis ...; 关键词：rheumatoid arthritis mast cells DEGRANULATION TLR4

The amino acids differences in epitopes may promote the different allergenicity of ovomucoid derived from hen eggs and quail eggs: 《Food Science and Human Wellness》2023年第3期861-870,共10页Mengzhen Hao Shuai Yang Shiwen Han Huilian Che; supported by the Beijing Municipal Natural Science Foundation of China(7202100)。; Quail egg ovomucoid can inhibit activation of basophils and eosinophils,while hen egg ovomucoid has been shown to be a major allergen,named Gal d 1.At present,the differences in structure and function between two ovom...; 关键词：Quail egg Hen egg OVOMUCOID Epitope DEGRANULATION

SARS-CoV-2-triggered mast cell rapid degranulation induces alveolar epithelial inflammation and lung injury被引量：3: 《Signal Transduction and Targeted Therapy》2022年第1期295-309,共15页Meng-Li Wu Feng-Liang Liu Jing Sun Xin Li Xiao-Yan He Hong-Yi Zheng Yan-Heng Zhou Qihong Yan Ling Chen Guo-Ying Yu Junbiao Chang Xia Jin Jincun Zhao Xin-Wen Chen Yong-Tang Zheng Jian-Hua Wang; SARS-CoV-2 infection-induced hyper-inflammation links to the acute lung injury and COVID-19 severity.Identifying the primary mediators that initiate the uncontrolled hypercytokinemia is essential for treatments.Mast c...; 关键词：INFLAMMATION LUNG ALVEOLAR

Fine-tuning Mast Cells is Essential for the Maintenance and Regulation of the Systemic and Immune Homeostasis: 《Journal of Integrative Medicine（双语）》2021年第2期60-74,共15页Sylvia Frisancho-Kiss; During the past decades,populous expansion in mast cell scientific literature came forth with more,than forty-four thousand PubMed publications available to date.Such surge is due to the appreciation of the momentous ...; 关键词：Mast cells Evolution DEGRANULATION PROTEASE Endocrine disruptors Environmental pollutants FIBROSIS ALLERGY NEUROINFLAMMATION

PKM2 controls the degranulation of secondary and tertiary granules in neutrophils by phosphorylating SNAP-23: 《Cellular & Molecular Immunology》2021年第8期2048-2050,共3页Xinlei Sun Dong Wang Yan Wang Lei Ye Fujie Shi Shuang Qu Hongwei Liang Ke Zen; This work was supported by grants from the Ministry of Science and Technology of China(2018YFA0507100);the National Natural Science Foundation of China(31670917,31770981,32000634,and 81803626);the Natural Science Foundation of Jiangsu Province(BK20180556);the fellowship of China Postdoctoral Science Foundation(2018M630642).; Polymorphonuclear neutrophils(PMNs)possess multiple distinct types of cytoplasmic granules:secondary granules,tertiary granules,and azurophil granules[1].It has been suggested that PMN degranulation is controlled by e...; 关键词：PKM2 NEUTROPHILS TERTIARY

Morphofunctional Properties of Human Platelets, Treated with Low Doses of Hydrogen Peroxide: 《Journal of Biosciences and Medicines》2020年第9期125-130,共6页Maksim S. Makarov Maya V. Storozheva; We studied morphofunctional properties of human platelets, treated with low doses of hydrogen peroxide (H₂O₂). It was shown that platelet incubation with 20 - 75 μM H₂O_2...; 关键词：PLATELETS GRANULES LAMELLA DEGRANULATION STABILIZATION

Comparison of the Biological Activity and Constituents in Japanese Ambers: 《Advances in Biological Chemistry》2020年第3期99-112,共14页Eisaku Shimizu Nozomu Shimoda Tetsuaki Kawamura Naomi Ueda Ken-ichi Kimura; Background/Aim: Kuji amber is an interesting natural source for drug discovery; 关键词：Japanese Ambers Kujigamberol Growth Restoration of a Mutant Yeast Inhibition of Degranulation RBL-2H3 Cells

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