BIOTIN

作品数:67被引量:71H指数:5
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Biotin-Thiamine-Responsive Basal Ganglia Disease: Clinical Features, Treatment Response and Predictive Factors in a Cohort in a Tertiary Hospital
《World Journal of Neuroscience》2025年第1期58-72,共15页Talal Alwahhabi Faris Alzhrany Mohammed Alzhrany Sadia Tabassum 
Introduction: Biotin-thiamine-responsive basal ganglia disease (BTBGD) is a neuroregressive disorder associated with subacute encephalopathy, confusion, dysarthria, and dysphagia, as well as occasional external ophtha...
关键词:Biotin-Thiamin-Responsive Basal Ganglia Disease Neuroregression Neurometabolic BIOTIN THIAMINE 
High-dose biotin neither fosters remyelination nor stimulates malonyl coenzyme A synthesis in the regenerating nerve
《Neural Regeneration Research》2023年第7期1623-1624,共2页Fabian Szepanowski Rebecca D.Steubing Cansu Güngör Jaqueline Zipfel Anne K.Mausberg Christoph Kleinschnitz Mark Stettner 
Dear editor,Dysregulated inflammatory responses primarily account for damage to the central nervous system,however,neurodegenerative processes likely contribute to the pathophysiology of progressive forms of multiple ...
关键词:system SYNTHESIS NEITHER 
A pretargeting nanoplatform for imaging and enhancing anti-inflammatory drug delivery被引量:1
《Bioactive Materials》2020年第4期1102-1112,共11页Min Kyung Khang Jun Zhou Cynthia M.Co Shuxin Li Liping Tang 
This work details a newly developed“sandwich”nanoplatform via neutravidin-biotin system for the detection and treatment of inflammation.First,biotinylated-and folate-conjugated optical imaging micelles targeted acti...
关键词:Polymeric micelles Neutravidin/biotin system PRETARGETING MACROPHAGES DEXAMETHASONE Inflammatory responses 
Intracellular Self-assembly of TPE-biotin Nanoparticles Enables Aggregation-Induced Emission Fluorescence for Cancer-Targeted Imaging
《Chinese Journal of Chemical Physics》2018年第6期851-856,734,共7页Yi-fei Xu Jin-hui Jiang 
supported by Anhui Scientific and Technological Project(No.1704a0802164);the Natural Science Foundation of the Anhui Higher Education Institutions of China(No.KJ2018A0192)
Fluorogens with aggregation-induced emission (AIE) characteristics have recently been widely applied for studying biological events, and fluorogens with “smart” properties are especially desirable. Herein, we ration...
关键词:TETRAPHENYLETHYLENE BIOTIN SELF-ASSEMBLY Aggregation-induced emission 
Application of Fuzzy Logic Algorithm to Single-Molecule Force Spectroscopy of the Streptavidin-Biotin System
《Advances in Materials Physics and Chemistry》2018年第5期217-226,共10页Hiroyuki Tahara Takashi Nyu Evan Angelo Quimada Mondarte Tatsuhiro Maekawa Tomohiro Hayashi 
The rupture force of the streptavidin-biotin complex was investigated using atomic force microscopy (AFM). The most frequently observed rupture force (MFOF), which is essential for the evaluation of the potential land...
关键词:SINGLE-MOLECULE FORCE Spectroscopy ATOMIC FORCE Microscopy Fuzzy Logic ALGORITHM STREPTAVIDIN BIOTIN 
Metabolic pathways as possible therapeutic targets for progressive multiple sclerosis被引量:1
《Neural Regeneration Research》2017年第8期1262-1267,共6页Rebecca M.Heidker Mitchell R.Emerson Steven M.Le Vine 
Unlike relapsing remitting multiple sclerosis, there are very few therapeutic options for patients with progressive forms of multiple sclerosis. While immune mechanisms are key participants in the pathogenesis of rela...
关键词:acetyl-coenzyme A carboxylase BIOTIN ESTROGEN IRON Kynurenine pathway MITOCHONDRIA thyroidhormone REMYELINATION stem cells vitamin D 
生物素靶向显影探针Biotin-S-S-Rhodol对乳腺癌细胞的靶向显影作用
《南方医科大学学报》2017年第1期124-129,共6页吴碧娟 周杏子 孙婧雯 谭翠雯 吴新荣 
广东省科技计划项目(2011A080300004);广州市科技计划项目(201509010012)
目的对新型生物素靶向显影探针(Biotin-S-S-Rhodol,3a)的靶向显影性能进行分析。方法采用紫外吸收光谱和荧光光谱分析谷胱甘肽(GSH)处理后3a的光谱特性;采用不同浓度GSH处理3a,荧光光谱分析3a对GSH的敏感性;采用流式细胞术和荧光倒置显...
关键词:Biotin-S-S-Rhodol 生物素 罗丹明 二硫键 靶向显影 乳腺癌 
Effect of surface ligand density on cytotoxicity and pharmacokinetic profile of docetaxel loaded liposomes被引量:2
《Asian Journal of Pharmaceutical Sciences》2016年第5期655-661,共7页Chun Chu Ping Xu Haoyue Zhao Qing Chen Dawei Chen Haiyang Hu Xiuli Zhao Mingxi Qiao 
Various biotin-modified liposomes incorporated with docetaxel(DTX) were prepared to study the effect of surface biotin density on the pharmacokinetic profile of the liposome. Four types of liposomes such as PEG modifi...
关键词:DOCETAXEL Liposomes BIOTIN LIGAND density TUMOR TARGETING 
Post-Marketing Surveillance of Fixed Dose Combination of Methylcobalamin, Alpha Lipoic Acid, Folic Acid, Biotin, Benfotiamine &Vitamin B6-Nutripathy for the Management of Peripheral Neuropathy被引量:1
《Journal of Diabetes Mellitus》2014年第2期124-132,共9页Manish Maladkar Chitra Tekchandani Urja Dave 
Background: Peripheral neuropathy is a commonly encountered troublesome condition which is often disabling & worsens when left untreated. Traditional neuropathic pain medications primarily provide symptomatic relief;h...
关键词:Peripheral NEUROPATHY METHYLCOBALAMIN Alpha Lipoic ACID Folic ACID BIOTIN BENFOTIAMINE VITAMIN B6 
Total synthesis of dansyl and biotin functionalized ganglioside GM3 by chemoenzymatic method被引量:1
《Science China Chemistry》2013年第7期933-938,共6页SUN Bin JIANG HeYan 
supported by Chongqing Municipal Commission of Education(KJ110704);Chongqing Technology & Business University (2010-56-01);Natural Science Foundation Project of CQ CSTC (2010BB5083);Chongqing Innovative Research Team Development Program in University(KJTD201020)
Ganglioside GM3, as well as other gangliosides, offers a variety of modifications in its sialic acid and ceramide moieties GM3 exhibits various types of important biological activities, due to the inability to effecti...
关键词:fluorescence BIOTIN chemoenzymatic synthesis ganglioside GM3 
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