云南高校图书馆联盟文献共享服务平台- INTERLEUKIN-1Β

INTERLEUKIN-1Β: 作品数：160被引量：867H指数：15; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：孙汭田志刚魏海明陈永艳侯晓东更多>>; 相关机构：山东大学中国科学技术大学四川大学华西医院中国科学院广州生物医药与健康研究院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省医学科学技术研究基金中国博士后科学基金更多>>

Homer1a reduces inflammatory response after retinal ischemia/reperfusion injury被引量：1: 《Neural Regeneration Research》2024年第7期1608-1617,共10页Yanan Dou Xiaowei Fei Xin He Yu Huan Jialiang Wei Xiuquan Wu Weihao Lyu Zhou Fei Xia Li Fei Fei; supported by the Youth Development Project of Air Force Military Medical University,No.21 QNPY072;Key Project of Shaanxi Provincial Natural Science Basic Research Program,No.2023-JC-ZD-48(both to FF)。; Elevated intraocular pressure(IOP)is one of the causes of retinal ischemia/reperfusion injury,which results in NRP3 inflammasome activation and leads to visual damage.Homerla is repo rted to play a protective role in ...; 关键词：CASPASE-8 Homer1a INTERLEUKIN-18 INTERLEUKIN-1Β intraocular pressure ischemia/reperfusion injury JSH-23 Müller cells NLRP3 nuclear factor-kB p65 RETINA

Suppressing high mobility group box-1 release alleviates morphine tolerance via the adenosine5'-monophosphate-activated protein kinase/heme oxygenase-1 pathway被引量：1: 《Neural Regeneration Research》2023年第9期2067-2074,共8页Tong-Tong Lin Chun-Yi Jiang Lei Sheng Li Wan Wen Fan Jin-Can Li Xiao-Di Sun Chen-Jie Xu Liang Hu Xue-Feng Wu Yuan Han Wen-Tao Liu Yin-Bing Pan; supported by the National Natural Science Foundation of China;Nos.81971047 (to WTL) and 82073910 (to XFW);the Natural Science Foundation of Jiangsu Province,No.BK20191253 (to XFW);Key R&D Program (Social Development) Project of Jiangsu Province,No.BE2019 732 (to WTL);Jiangsu Province Hospital (the First Affiliated Hospital of Nanjing Medical University) Clinical Capacity Enhancement Project,No.JSPH-511B2018-8 (to YBP)。; Opioids,such as morphine,are the most potent drugs used to treat pain.Long-term use results in high tolerance to morphine.High mobility group box-1(HMGB1) has been shown to participate in neuropathic or inflammatory p...; 关键词：adenosine 5’-monophosphate-activated protein kinase heme oxygenase-1 high mobility group box-1 INTERLEUKIN-1Β MICROGLIA morphine tolerance NEUROINFLAMMATION neuron nuclear factor-κB p65 Toll-like receptor 4

Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects被引量：1: 《Neural Regeneration Research》2023年第5期1118-1123,共6页Han-Jun Qin Hang Li Jun-Ze Chen Kai-Rui Zhang Xing-Qi Zhao Jian-Qiang Qin Bin Yu Jun Yang; supported by Military Medical Science&Technology Youth Training Program,No. 19QNP005;President Foundation of Nanfang Hospital,Southern Medical University,No. 2020B028 (both to JY)。; Studies have shown that human hair keratin(HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secr...; 关键词：artificial nerve graft bioactive human hair keratin INTERLEUKIN-1Β MACROPHAGES nerve graft nerve growth factor nerve repair peripheral nervous injury Schwann cells

Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization: 《Neural Regeneration Research》2023年第5期1132-1138,共7页Yong Yu Li-Kun Xia Yu Di Qing-Zhu Nie Xiao-Long Chen; supported by the National Natural Science Foundation of China,No. 81570866 (to XLC)。; Inhibiting retinal neovascularization is the optimal strategy for the treatment of retina-related diseases, but there is currently no effective treatment for retinal neovascularization. P-element-induced wimpy testis(...; 关键词：angiogenesis human retinal endothelial cells hypoxia inducible factor-1α HYPOXIA INTERLEUKIN-1Β migration non-coding RNA oxygen-induced injury PIWI-interacting RNA RETINOPATHY

Early brainstem hemorrhage progression:multi-sequence magnetic resonance imaging and histopathology: 《Neural Regeneration Research》2023年第1期170-175,共6页Xi Guo Jia-Ke Xu Xin Qi Yang Wei Cheng-Wei Wang Hao Li Lu Ma Chao You Meng Tian; supported by the Natural Science Foundation of Xinjiang Uygur Autonomous Region, No. 2020D01A13 (to CWW);Chengdu Science and Technology Bureau, No. 2019-YF05-00511-SN (to MT);1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University, Nos. ZY2016102 (to MT), and ZY2016203 (to CY); According to clinical statistics,the mortality of patients with early brainstem hemorrhage is high.In this study,we established rat models of brainstem hemorrhage by injecting type Ⅶ collagenase into the right basote...; 关键词：brainstem hemorrhage diffuse tensor imaging diffusion-weighted imaging Fluoro-Jade C staining hematoxylin-eosin staining INTERLEUKIN-1Β luxol fast blue rat model T2-weighted imaging tumor necrosis factor-α

Interleukin-1:an important target for perinatal neuroprotection?: 《Neural Regeneration Research》2023年第1期47-50,共4页Sharmony B.Kelly Elys Green Rod W.Hunt Claudia A.Nold-Petry Alistair J.Gunn Marcel F.Nold Robert Galinsky; supported by the CJ Martin Postdoctoral Fellowship;grants from the National Health and Medical Research Council of Australia (1090890 and 1164954);the Cerebral Palsy Alliance, Harold and Cora Brennen Benevolent Trust, Health Research Council of New Zealand (17/601);the Victorian Government’s Operational Infrastructure Support Program (to RG); Perinatal inflammation is a significant risk factor for lifelong neurodevelopmental impairments such as cerebral palsy.Extensive clinical and preclinical evidence links the severity and pattern of perinatal inflammati...; 关键词：brain INFLAMMATION interleukin-1 receptor antagonist INTERLEUKIN-1 INTERLEUKIN-1Β neonatal encephalopathy NEUROPROTECTION preterm brain injury

Involvement of NLRP3-inflammasome pathway in noise-induced hearing loss被引量：4: 《Neural Regeneration Research》2022年第12期2750-2754,共5页Na Sai Yuan-Yuan Yang Long Ma Da Liu Qing-Qing Jiang Wei-Wei Guo Wei-Ju Han; supported by the National Key Research and Development Program of China, No.2020YFC2005200(to WWG and WJH);the National Nature Science Foundation of China, Nos.81770992(to NS and WJH), 81970897(to WWG);Health and Family Planning System Research Project of Shenzhen Municipality, No.SZXJ2018079(to YYY);Shenzhen Sanming Project, No.SZSM201612076(to YYY); The inflammasome is a multiprotein oligomer in the cell cytoplasm and is part of the innate immune system.It plays a crucial role in the pathological process of noise-induced hearing loss(NIHL).However,the mechanisms ...; 关键词：acoustic injury INFLAMMASOME INTERLEUKIN-1Β miniature pig NLR family pyrin domain containing 3(NLRP3) noise-induced hearing loss sensorineural hearing loss

MicroRNA-101a-3p mimic ameliorates spinal cord ischemia/reperfusion injury被引量：3: 《Neural Regeneration Research》2022年第9期2022-2028,共7页Zai-Li Zhang Dan Wang Feng-Shou Chen; miR-101a-3p is expressed in a variety of organs and tissues and plays a regulatory role in many diseases,but its role in spinal cord ischemia/reperfusion injury remains unclear.In this study,we established a rat model...; 关键词：apoptosis CASPASE-9 INFLAMMATION INTERLEUKIN-1Β microRNA-101a-3p MYCN nerve cells p53 spinal cord ischemia/reperfusion injury

Leukocyte telomere length and plasma interleukin-1β and interleukin-18 levels in mild cognitive impairment and Alzheimer's disease: new biomarkers for diagnosis and disease progression?被引量：3: 《Neural Regeneration Research》2021年第7期1397-1398,共2页Rosa Maria Corbo Rita Businaro Daniela Scarabino; supported by Sapienza University of Rome (2017/2018 grants allotted to RB and RMC)。; Alzheimer's disease and mild cognitive impairment biomarkers: Alzheimer's disease(AD) is a progressive neurodegenerative disease of advancing age.It affects around 47 million people in the world and the number is esti...; 关键词：ALZHEIMER IMPAIRMENT DIAGNOSIS

The NLRP3 inflammasome: a potential therapeutic target for traumatic brain injury被引量：9: 《Neural Regeneration Research》2021年第1期49-57,共9页Saifudeen Ismael Heba A.Ahmed Tusita Adris Kehkashan Parveen Parth Thakor Tauheed Ishrat; supported by the Department of Anatomy Neurobiology,UTHSC Memphis TN(to TI);National Institute of Health,No.R01-NS097800(to TI)。; Although the precise mechanisms contributing to secondary brain injury following traumatic brain injury are complex and obscure,a number of studies have demonstrated that inflammatory responses are an obvious and earl...; 关键词：INFLAMMATION INTERLEUKIN-1Β NLRP3-inflammasome CASPASE-1 MCC950 traumatic brain injury

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