AUTOCRINE

作品数：41被引量：161H指数：7
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相关作者：朱华宇胡大海孙长伏赵震锦更多>>
相关机构：第四军医大学纽约州立大学中国医科大学更多>>
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Autocrine IL-8 Contributes to Propionibacterium Acnes-induced Proliferation and Differentiation of HaCaT Cells via AKT/FOXO1/Autophagy
《Current Medical Science》2024年第5期1058-1065,共8页Xiu-qin YU Jin-zhu MAO Shu-yun YANG Lu WANG Chang-zhi YANG Lei HUANG Qi-hong QIAN Ting-ting ZHU 
supported by the National Natural Science Foundation of China(No.82103756).
Objective Proprionibacterium acnes(P.acnes)-induced inflammatory responses,proliferation and differentiation of keratinocytes contribute to the progression of acne vulgaris(AV).P.acnes was found to enhance the product...
关键词：acne vulgaris Proprionibacterium acnes KERATINOCYTE INTERLEUKIN-8 C-X-C motif chemokine receptor 2 protein kinase B forkhead box O1 AUTOPHAGY 
The secretory function of adipose tissues in metabolic regulation被引量：1
《Life Metabolism》2024年第2期9-23,共15页Yang Liu Shu-Wen Qian Yan Tang Qi-Qun Tang 
supported by the National Key R&D Program of China(grant 2018YFA0800400 to Q.Q.T.);the National Natural Science Foundation of China(NSFC)(grants 82370881,82170884,and 81970744 to Y.L.);Shanghai Rising-Star Program(grant 22QA1402100 to Y.L.).
In addition to their pivotal roles in energy storage and expenditure,adipose tissues play a crucial part in the secretion of bioactive molecules,including peptides,lipids,metabolites,and extracellular vesicles,in resp...
关键词：ADIPOKINES AUTOCRINE PARACRINE ENDOCRINE metabolic regulation 
Crosstalk between glioblastoma and tumor microenvironment drives proneural–mesenchymal transition through ligand-receptor interactions被引量：1
《Genes & Diseases》2024年第2期874-889,共16页Yancheng Lai Xiaole Lu Yankai Liao Pei Ouyang Hai Wang Xian Zhang Guanglong Huang Songtao Qi Yaomin Li 
supported by the National Natural Science Foundation of China(No.82203368);Science and Technology Projects in Guangzhou,Guangdong,China(No.202201011008);College Students'Innovative Entrepreneurial Training Plan Program,China(No.202112121201).
Glioblastoma(GBM)is the most common intrinsic and aggressive primary brain tumor in adults,with a median survival of approximately 15 months.GBM heterogeneity is considered responsible for the treatment resistance and...
关键词：AUTOCRINE GLIOBLASTOMA Ligand-receptor interaction MICROENVIRONMENT PARACRINE Proneural-mesenchymal transition 
Dl-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog被引量：5
《Acta Pharmacologica Sinica》2023年第12期2404-2417,共14页Mei-jie Dai Xing-xing Gui Shu-miao Jia Shu-ting Lv Hao Dou Wei Cui 
the key program of the Educational Department of Liao Ning Province(Nos.LJKZZ20220100).
Dl-3-n-butylphthalide(NBP)is a small-molecule drug used in the treatment of ischemic stroke in China,which is proven to ameliorate the symptoms of ischemic stroke and improve the prognosis of patients.Previous studies...
关键词：ischemic stroke ANGIOGENESIS Dl-3-n-butylphthalide brain ischemia/reperfusion tMCAO model hedgehog signaling pathway 
Kupffer cell restoration after partial hepatectomy is mainly driven by local cell proliferation in IL-6-dependent autocrine and paracrine manners被引量：2
《Cellular & Molecular Immunology》2021年第9期2165-2176,共12页Yeni Ait Ahmed Yaojie Fu Robim M.Rodrigues Yong He Yukun Guan Adrien Guillot Ruixue Ren Dechun Feng Juan Hidalgo Cynthia Ju Fouad Lafdil Bin Gao 
This work was supported by the intramural program of the NIAAA(Bin Gao);the NIH grant R01DK121330,R01DK 122708,R01DK122796(Cynthia Ju);the Institut Universitaire de France(Fouad Lafdil);the Ministerio de Economía y Competitividad and European Regional Development Fund RTI2018-101105-B-100(Juan Hidalgo).
Kupffer cells(KCs),which are liver-resident macrophages,originate from the fetal yolk sac and represent one of the largest macrophage populations in the body.However,the current data on the origin of the cells that re...
关键词：IL-6 Sirtuin 1 Liver regeneration Kupffer cells Myeloid cells 
What group 2 innate lymphoid cells tell themselves:autocrine signals play essential roles in mucosal immunity被引量：1
《Signal Transduction and Targeted Therapy》2021年第8期2264-2265,共2页Yang Zhao Wenxian Guan Xiaofei Shen 
This work was supported by the National Natural Science Foundation of China(number 81970500,X.S.,number 81802846,YZ.);the Natural Science Foundation of Jiangsu Province(SBK2018040809,YZ.).
Recently,two article papers(Chu et al.1 and Roberts et al.2)were published describing that autocrine regulation mediated by the choline acetyltransferase(ChAT)-acetylcholine(ACh)is critical for optimal Group 2 innate ...
关键词：IMMUNITY LYMPHOID 
Glucocorticoids Inducing Vascular Repair Disorders under Hypoxia via Inhibiting Cell Migration and Autocrine/paracrine:Bioinformatical Analysis Combined with Cytological Experiment
《Chinese Journal of Biomedical Engineering(English Edition)》2021年第2期75-92,共18页MA Jun YANG Pei WANG Kun-zheng 
the National Natural Science Foundation of China;grant number:81301562 and 81572147。
The exact molecular and cytological mechanism of how glucocorticoids induce vascular repair disorders in glucocorticoid-induced avascular necrosis of the femoral head is still unclear.We used bioinformatical tools for...
关键词：vascular repair disorders HYPOXIA endothelial cells glucocorticoid-induced osteonecrosis bioinformatical analysis 
Endothelin increases the proliferation of rat olfactory mucosa cells
《Neural Regeneration Research》2020年第2期352-360,共9页Bertrand Bryche Audrey Saint-Albin Claire Le Poupon Schlegel Christine Baly Patrice Congar Nicolas Meunier 
funded by the Institut National de la Recherche Agronomique(INRA)
The olfactory mucosa holds olfactory sensory neurons directly in contact with an aggressive environment. In order to maintain its integrity, it is one of the few neural zones which are continuously renewed during the ...
关键词：AUTOCRINE factor cell CULTURE cellular dynamics ENDOTHELIN OLFACTION OLFACTORY basal CELLS OLFACTORY epithelium OLFACTORY mucosa primary CULTURE 
New insights into autocrine cytokines produced by ischemic cardiomyocytes and ventricular remodeling
《Science China(Life Sciences)》2015年第9期915-917,共3页YU Xian LIAO YuHua 
supported by the National Basic Research Program of China(2007CB512000,2007CB512005)
Ischemic heart disease is one of the leading causes of death in the world. Although modern therapy of acute myocardial infarction （AMI） can reduce infarct size and result in an increased early survival rate, heart f...
关键词：炎性细胞因子 缺血性心脏病 心肌细胞 心室重构 自分泌 急性心肌梗死 心力衰竭 NF-κB 
Blocking autocrine VEGF signaling by sunitinib, an anti-cancer drug, promotes embryonic stem cell selfrenewal and somatic cell reprogramming被引量：8
《Cell Research》2014年第9期1121-1136,共16页Guofang Chen Xinxiu Xu Lihong Zhang Yanbin Fu Min Wang Haifeng Gu Xin Xie 
Maintaining the self-renewal of embryonic stem cells （ESCs） could be achieved by activating the extrinsic signaling, i.e., the use of leukemia inhibitory factor （LIF）, or blocking the intrinsic differentiation pat...
关键词：SUNITINIB Sutent embryonic stem cell SELF-RENEWAL IPSC VEGF AUTOCRINE 
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