云南高校图书馆联盟文献共享服务平台- YOHIMBINE

YOHIMBINE: 作品数：14被引量：50H指数：3; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：丁晓琴陈冀胜赵立峰丁俊杰更多>>; 相关机构：北京药物化学研究所中山大学西安交通大学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Chinese Medical Journal》《物理化学学报》更多>>; 相关基金：国家自然科学基金更多>>

Dexmedetomidine Promotes Angiogenesis and Vasculogenic Mimicry in Human Hepatocellular Carcinoma through α^(2)-AR/HIF-1α/VEGFA Pathway被引量：2: 《Biomedical and Environmental Sciences》2022年第10期931-942,共12页FANG Tao LIN Li YE Zhi Jian FANG Lian SHI Shuai YU Ke Da MIAO Hui Hui LI Tian Zuo; supported by the Natural Science Foundation of Zhejiang Province[LY19H160002];the Science and Technology Research Program of Jinhua City[2018-3-001b and 2017-3-020]; Objective Dexmedetomidine(DEX),the most specificα^(2)-adrenergic receptor agonist widely used for its sedative and analgesic properties,has been reported to upregulate HIF-1αexpression to protect hypoxic and ischemi...; 关键词：Hepatocellular carcinoma DEXMEDETOMIDINE YOHIMBINE α^(2)-adrenergic receptor HIF-1A VEGFA Vascular mimicry ANGIOGENESIS

Synthetic studies towards(-)-deserpidine:Total synthesis of the stereoisomer and derivative of (-)-deserpidine: 《Chinese Chemical Letters》2021年第1期401-404,共4页Pingzhou Wu Qilong Zhou Xiao-Yu Liu Fei Xue Yong Qin; the financial surpport from the National Natural Science Foundation of China(Nos.21702140 and21732005);National Science and Technology Major Projects for“Major New Drugs Innovation and Development”(No.2018ZX09101003-005-004)。; The asymmetric synthesis of 16,17,20-epi-deserpidine and a derivative of(-)-deserpidine has been achieved.Key feature s in the assembly of the pentacyclic framework include a visible-light photocatalytic intra-/inter-...; 关键词：Yohimbine alkaloids Deserpidine Photoredox catalytic radical cascade reaction Total synthesis

The Effect of Tramadol on Blood Glucose Levels in Rats: 《Open Journal of Anesthesiology》2013年第1期18-22,共5页Hacer Kara Ayse Karci Mukaddes Gumustekin Murat Ormen Aydin Tasdogen Zahide Elar; The Background: Tramadol, is a central acting analgesic that possesses weak affinity for the μ-opioid receptor and modifies transmission of nociceptive impulses through inhibition of monoamine reuptake. This study wa...; 关键词：HYPERGLYCEMIA TRAMADOL a2Antagonist Antinociceptive Effect YOHIMBINE IDAZOXAN RAT

Effects of methanolic extract of <i>Pausinystalia yohimbe</i>bark on blood glucose level in normal fasting rats被引量：1: 《Health》2012年第12期1225-1228,共4页Hozeifa Mohamed Hassan Taj Eldin Imad Mohamed Elhadi Mohamed Mohamed Ahmed Abd Elwahab Hassan Mohamed Nizar Sirag; Background: Pausinystalia yohimbe (L.) is a member of the family Rubiaceae. It is a valuable medicinal tree, distributed in evergreen closed-canopy forests in West Africa. It is traditionally used for treatment of ere...; 关键词：Pausinystalia yohimbe BARK YOHIMBINE FASTING Blood Glucose Level HYPOGLYCEMIA

Berberine protects against lipopolysaccharide- induced intestinal injury in mice via alpha 2 adrenoceptor-independent mechanisms被引量：32: 《Acta Pharmacologica Sinica》2011年第11期1364-1372,共9页Hong-mei LI Yi-yang WANG Hua-dong WANG Wen-juan CAO Xiao-hui YU Da-xiang LU Ren-bin QI Chao-feng HU Yu-xia YAN; Aim： To investigate the mechanisms responsible for the protective action of berberine （Ber） against gut damage in endotoxemic mice. Methods： Male BALB/c mice were administered intragastrically with distilled water...; 关键词：BERBERINE LIPOPOLYSACCHARIDE intestinal injury apoptosis Toll-like receptor 4 （TLR4） NF-KB macrophage inflammatoryprotein-2 （MIP-2） a2-adrenoceptor YOHIMBINE

Yohimbine protects against endotoxin-induced acute lung injury by blockade of alpha 2A adrenergic receptor in rats被引量：3: 《Chinese Medical Journal》2011年第7期1069-1074,共6页LIN Ying ZHU Xi YAO Wan-zhen YANG Yan-lin A La-ta CHEN Li; Background Alpha 2A adrenergic receptor （AR） is a subtype of （]2 AR belonging to G protein-coupled receptors, and exerts a variety of biological effects. Recent studies have demonstrated that the a2A AR activation ...; 关键词：acute lung injury a2A adrenergic receptor inflammatory response

Effects of α-adrenoreceptor antagonists on apoptosis and proliferation of pancreatic cancer cells in vitro被引量：1: 《World Journal of Gastroenterology》2008年第15期2358-2363,共6页Su-Gang Shen Dong Zhang Heng-Tong Hu Jun-Hui Li Zheng Wang Qing-Yong Ma; The Natural Science Foundation of Shaanxi Province, No. 2006C209; AIM: To discuss the expression of α-adrenoreceptors in pancreatic cancer cell lines PC-2 and PC-3 and the effects of α1- and α2-adrenoreceptor antagonists, yohimbine and urapidil hydrochloride, on the cell lines in...; 关键词：Alpha-adrenoreceptor Pancreatic cancer YOHIMBINE Urapidil hydrochloride

Yohimbine in the treatment of orgasmic dysfunction被引量：2: 《Asian Journal of Andrology》2007年第3期403-407,共5页Ade A. Adeniyi Giles S. Brindley John P. Pryor David J. Ralph; Aim： To study the effect of yohimbine in the treatment of men with orgasmic dysfunction. Methods： A 20-mg dose of yohimbine was first given to 29 men with orgasmic dysfunction of different aetiology in the clinic. P...; 关键词：YOHIMBINE anorgasmia ORGASM orgasmic dysfunction IMPOTENCE EJACULATION

Effects of intrathecal 6-hydroxydopamine,α_1 and α_2 adrenergic receptor antagonists on antinociception of propofol in mice被引量：5: 《Acta Pharmacologica Sinica》2005年第2期186-191,共6页Zhi-junGE Yin-mingZENG Yong-feiTAN; Aim:To investigate the relationship between spinal cord norepinephrine,α_1 and α_2 adrenergic receptors and antinociception of propofol in mice.Methods: Kunming mice were used.Antinociceptive tests were investigated...; 关键词：PROPOFOL spinal cord ANTINOCICEPTION prazosin yohimbine norepinephrine

α2A-肾上腺素受体的同源模建及与Yohimbine的对接研究被引量：2: 《物理化学学报》2005年第2期151-155,共5页赵立峰丁晓琴丁俊杰陈冀胜; 通过对比多个与α2A-肾上腺素受体同属G-蛋白偶联受体的视紫红质蛋白序列,选择以相似性最大的牛视紫红质蛋白为模板,同源模建了α2A-肾上腺素受体的跨膜结构,并在结构中找到了体积为0.090nm3,已被报导的活性残基包围的活性位点.运用分...; 关键词：跨膜蛋白 α2A-肾上腺素受体同源模建对接 YOHIMBINE

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