IRRITABLE

作品数：153被引量：1654H指数：17
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相关领域：医药卫生更多>>
相关作者：张声生汪正芳郭前坤魏玮蒋欢欢更多>>
相关机构：首都医科大学附属北京中医医院中华中医药学会中国中医科学院望京医院河北北方学院附属第二医院更多>>
相关期刊：《Psychosomatic Medicine Research》《Chinese Medical Journal》《外科研究与新技术（中英文）》《Precision Medicine Research》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>
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Ethnic differences in genetic polymorphism associated with irritable bowel syndrome被引量：6
《World Journal of Gastroenterology》2020年第17期2049-2063,共15页Qi-Yun Xiao Xiu-Cai Fang Xiao-Qing Li Gui-Jun Fei 
Supported by the Program of International S&T Cooperation,No.2014DFA31850;National Natural Science Foundation of China,No.81870379.
Genetic polymorphism is associated with irritable bowel syndrome(IBS)in terms of susceptibility and clinical manifestations.Previous studies have shown that genetic polymorphism might play a key role in the onset and ...
关键词：IRRITABLE BOWEL syndrome ETHNICITY Genetic POLYMORPHISM Single NUCLEOTIDE POLYMORPHISM Genome-wide association Pathogenesis 
Altered profiles of fecal metabolites correlate with visceral hypersensitivity and may contribute to symptom severity of diarrhea-predominant irritable bowel syndrome被引量：10
《World Journal of Gastroenterology》2019年第43期6416-6429,共14页Wen-Xue Zhang Yu Zhang Geng Qin Kai-Min Li Wei Wei Su-Yun Li Shu-Kun Yao 
the National Key Technology Support Program for the “12th Five-Year Plan” of China,No.2014BAI08B00;the Research Projects on Biomedical Transformation of China-Japan Friendship Hospital,No.PYBZ1815
BACKGROUND Fecal metabolites are associated with gut visceral sensitivity,mucosal immune function and intestinal barrier function,all of which have critical roles in the pathogenesis of irritable bowel syndrome(IBS).H...
关键词：FECAL metabolite IRRITABLE bowel syndrome Amino ACIDS Organic ACIDS Short chain fatty ACIDS VISCERAL HYPERSENSITIVITY 
Is there an association between Helicobacter pylori infection and irritable bowel syndrome? A meta-analysis被引量：5
《World Journal of Gastroenterology》2019年第37期5702-5710,共9页Qin Xiang Ng Nadine Xinhui Foo Wayren Loke Yun Qing Koh Vanessa Jing Min Seah Alex Yu Sen Soh Wee Song Yeo 
BACKGROUND Irritable bowel syndrome(IBS)is a prevalent and debilitating gastrointestinal condition.Research has reported persistent,low-grade mucosal inflammation and significant overlaps between patients with IBS and...
关键词：IRRITABLE BOWEL SYNDROME Functional HELICOBACTER PYLORI INFECTION Metaanalysis 
Effect of Tong Xie Yao Fang on endogenous metabolites in urine of irritable bowel syndrome model rats被引量：17
《World Journal of Gastroenterology》2019年第34期5134-5151,共18页Xue-Ying Zhao Jian-Wei Wang Yue Yin Kai Li Miao Zhang Fu-Ping Yan 
Supported by the National Natural Science Foundation of China,No.81573870;the Eighth Special Subsidy Project of China Post Doctoral Science Foundation,No.2015T80376;Postdoctoral Science Research Developmental Foundation of China,No.2013M531079;National Science Foundation of Heilongjiang Province,No.H2015020;Heilongjiang University of Traditional Chinese Medicine Outstanding Innovative Talents Support Project(Outstanding Young Academic Leaders),Postdoctoral Science-Research Developmental Foundation of Heilongjiang Province,No.LBHQ12009;Youth Academic Backbone Fund of Heilongjiang Province Education Department,No.1253G053;Youth Science and Technology Project of Traditional Chinese Medicine Department of Heilongjiang Province,No.ZQG-034
BACKGROUND Tong Xie Yao Fang is a representative traditional Chinese prescription for the treatment of liver and spleen deficiency,abdominal pain and diarrhea.It has a unique function in the treatment of gastrointesti...
关键词：Tong Xie YAO Fang IRRITABLE BOWEL syndrome Liver-spleen disharmony ENDOGENOUS METABOLITES Metabolomics 
Clostridium butyricum alleviates intestinal low-grade inflammation in TNBS-induced irritable bowel syndrome in mice by regulating functional status of lamina propria dendritic cells被引量：25
《World Journal of Gastroenterology》2019年第36期5469-5482,共14页Qin Zhao Wen-Rong Yang Xiao-Hong Wang Gai-Qin Li Lei-Qi Xu Xiao Cui Yang Liu Xiu-Li Zuo 
Supported by the National Natural Science Foundation of China,No.81770538 and No.81570485;Key Research and Development Program of Shandong Province,No.2017CXGC1215
BACKGROUND Irritable bowel syndrome (IBS) is one of the most common functional gastroenterological diseases characterized by abnormal visceral sensitivity and lowgrade inflammation. The role of Clostridium butyricum (...
关键词：CLOSTRIDIUM butyricum IRRITABLE bowel syndrome LAMINA propria dendritic cells T cell immunoglobulin and MUCIN domain-3 PROINFLAMMATORY cytokines 
Berberine prevents stress-induced gut inflammation and visceral hypersensitivity and reduces intestinal motility in rats被引量：14
《World Journal of Gastroenterology》2019年第29期3956-3971,共16页Zhi-Chao Yu Yong-Xin Cen Ben-Hua Wu Cheng Wei Feng Xiong De-Feng Li Ting-Ting Liu Ming-Han Luo Li-Liangzi Guo Ying-Xue Li Li-Sheng Wang Jian-Yao Wang Jun Yao 
the National Natural Science Foundation of China,No.81800489;Shenzhen Health and Family Planning System Research Project,No.SZXJ2017030;Technical Research and Development Project of Shenzhen,Nos.JCYJ20170307100538697 and JCYJ20170307100911479
BACKGROUND Irritable bowel syndrome (IBS) is a common chronic non-organic disease of the digestive system. Berberine (BBR) has been used to treat patients with IBS, but the underlying therapeutic mechanism is little u...
关键词：IRRITABLE bowel syndrome Visceral hypersensitivity BERBERINE RIFAMPICIN Nuclear FACTOR KAPPA-B BRAIN-DERIVED neurotrophic FACTOR Cajal mesenchymal cells Ckit 
Effect of mild moxibustion on intestinal microbiota and NLRP6 inflammasome signaling in rats with post-inflammatory irritable bowel syndrome被引量：51
《World Journal of Gastroenterology》2019年第32期4696-4714,共19页Chun-Hui Bao Chun-Ye Wang Guo-Na Li Yi-Lu Yan Di Wang Xiao-Ming Jin Lu-Yi Wu Hui-Rong Liu Xiao-Mei Wang Zheng Shi Huan-Gan Wu 
Supported by the National Natural Science Foundation of China,No.81503656;the National Key Basic Research Program of China(973 Program),No.2015CB554501 and No.2009CB522900
BACKGROUND About one-third of refractory irritable bowel syndrome(IBS)cases are caused by gastrointestinal(GI)infection/inflammation,known as post-infectious/postinflammatory IBS(PI-IBS).Although it is known that inte...
关键词：Moxibustion Post-inflammation IRRITABLE bowel syndrome INTESTINAL microbes NLRP6 INFLAMMASOME INTESTINAL INFLAMMATION Visceral HYPERSENSITIVITY Traditional Chinese medicine 
Personalized medicine in functional gastrointestinal disorders:Understanding pathogenesis to increase diagnostic and treatment efficacy被引量：8
《World Journal of Gastroenterology》2019年第10期1185-1196,共12页Xiao Jing Wang Michael Camilleri 
There is overwhelming evidence that functional gastrointestinal disorders(FGIDs) are associated with specific mechanisms that constitute important targets for personalized treatment. There are specific mechanisms in p...
关键词：Gastrointestinal symptoms GASTRIC emptying GASTRIC accommodation DIARRHEA Constipation IRRITABLE bowel syndrome Bile acid DIARRHEA Phenotypes PHARMACOGENOMICS PROKINETICS NEUROMODULATORS 
Nutrient drink test: A promising new tool for irritable bowel syndrome diagnosis被引量：1
《World Journal of Gastroenterology》2019年第7期837-847,共11页Fermin Estremera-Arevalo Marta Barcelo Blanca Serrano Enrique Rey 
BACKGROUND Irritable bowel syndrome(IBS) is a highly prevalent condition. It is diagnosed on the basis of chronic symptoms after the clinical and/or investigative exclusion of organic diseases that can cause similar s...
关键词：IRRITABLE BOWEL syndrome NUTRIENT DRINK TEST Non-invasive DYSPEPSIA Screening 
Contribution of ghrelin to functional gastrointestinal disorders' pathogenesis被引量：18
《World Journal of Gastroenterology》2019年第5期539-551,共13页Tilemachos Koutouratsas Theodora Kalli Georgios Karamanolis Maria Gazouli 
Functional gastrointestinal disorders(FGID) are heterogeneous disorders with a variety of clinical manifestations, primarily defined by signs and symptoms rather than a definite underlying cause. Their pathophysiology...
关键词：FUNCTIONAL GASTROINTESTINAL disorders FUNCTIONAL colonic diseases IRRITABLE bowel SYNDROME Cyclic vomiting SYNDROME Infantile COLIC GASTROINTESTINAL disease GHRELIN Genetics Epigenetic processes 
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