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Regulation of lncRNA-ENST on Myc-mediated mitochondrial apoptosis in mesenchymal stem cells:In vitro evidence implicated for acute lung injury therapeutic potential
《World Journal of Stem Cells》2025年第3期65-80,共16页Ye-Zhou Shen Guang-Ping Yang Qi-Min Ma Yu-Song Wang Xin Wang 
Supported by the Peak Supporting Clinical Discipline of Shanghai Health Bureau,No.2023ZDFC0104;the National Key R&D Program of China,No.2019YFA0110601.
BACKGROUND Acute lung injury(ALI)is a fatal and heterogeneous disease.While bone marrow mesenchymal stem cells(BMSCs)have shown promise in ALI repair,their efficacy is compromised by a high apoptotic percentage.Prelim...
关键词:Long noncoding RNA Mesenchymal stem cell MITOCHONDRIAL Apoptosis AUTOPHAGY Acute lung injury 
Gene Expression Profile Identifies LncRNA AL355974.3 As a Potential Glioma Biomarker
《Current Medical Science》2024年第5期1047-1057,共11页Hao-tian LU Yu-yang CHEN Yong-jia YU Xing-sheng LIAO Hui LIANG Lun LIANG Pan-lin MO Xin-kai HUANG Shuai DING Chang LIU Da-qin FENG 
supported by grants from the National Natural Science Foundation of China(No.82260554);Natural Science Foundation of Guangxi Province(No.2023GXNSFBA026092 and No.2024GXNSFAA010100);Key Research and development Program of Guangxi Province(No.2023AB22116).
Objective Glioma is a central nervous system tumor arising from glial cells.Despite significant advances in diagnosis and treatment,most patients with high-grade gliomas have a poor prognosis.Many studies have shown t...
关键词:GLIOMA long noncoding RNAs BIOMARKER RNA sequencing 
Identification and characterization of long noncoding RNAs and their association with acquisition of blood meal in Culex quinquefasciatus被引量:1
《Insect Science》2021年第4期917-928,共12页Azali Azlan Mardani Abdul Halim Faisal Mohamad Ghows Azzam 
This study was funded by the Universiti Sains Malaysia Research University Grant(1001/PBIOLOGI/8011604);MOSTI Science-Fund(305/PBIOLOGI/613238).
The Southern house mosquito,Culex quinquefasciatus(Cx.quinquefasciatus)is an important vector that transmit multiple diseases including West Nile encephalitis,Japanese encephalitis,St.Louis encephalitis and lymphatic ...
关键词:Culex quinquefasciatus BLOOD-FEEDING long noncoding RNA TRANSCRIPTOME 
Regulation of noncoding RNAs in innate lymphoid cells
《Cellular & Molecular Immunology》2023年第5期543-545,共3页Benyu Liu Lingwei Zhang Pingping Zhu Zusen Fan 
the National Key R&D Program of China(2021YFA1302000,2020YFA0803501);the National Natural Science Foundation of China(32170874,81921003,31930036);Joint Funding of Henan Provincial ScienceandTechnologyR&DPlan(222301420015).
Innate lymphoid cells(ILCs)have been defined in recent years and are important effector cells against pathogens and critical regulators in maintaining tissue homeostasis[1].Noncoding RNAs(ncRNAs),such as circular RNAs...
关键词:LYMPHOID HOMEOSTASIS noncoding 
Magnetic iron oxide nanoparticles accelerate osteogenic differentiation of mesenchymal stem cells via modulation of long noncoding RNA INZEB2被引量:12
《Nano Research》2017年第2期626-642,共17页Qiwei Wang Bo Chen Fang Ma Shikang Lin Meng Cao Yan Li Ning Gu 
Nanomaterials are increasingly used for biomedical applications; thus, it is important to understand their biological effects. Previous studies suggested that magnetic iron oxide nanoparticles (IONPs) have tissue-re...
关键词:iron oxide nanoparticle mesenchymal stem cell osteogenic differentiation long noncoding RNA magnetogenetics nano-magnetic bioeffects 
The mitochondrial genome encodes abundant small noncoding RNAs被引量:3
《Cell Research》2013年第6期759-774,共16页Seungil Ro Hsiu-Yen Ma Chanjae Park Nicole Ortogero Rui Song Grant W Hennig Huili Zheng Yung-Ming Lin2 Loredana Moro Jer-Tsong Hsieh wei Yant 
Small noncoding RNAs identified thus far are all encoded by the nuclear genome. Here, we report that the murine and human mitochondrial genomes encode thousands of small noncoding RNAs, which are predominantly derived...
关键词:MITOCHONDRIA small noncoding RNAs RNA interference TRANSCRIPTION gene expression circular genome 
One Novel Long Noncoding RNA lnc10 in Drosophila被引量:1
《Journal of Genetics and Genomics》2014年第2期79-82,共4页Meixia Li Mengbo Xu Shengyun Wen Baoyan Bai Runsheng Chen Li Liu 
supported by the grants from the National Natural Science Foundation of China (No. 31300889)
With the development of computational methods and RNA sequencing technology for assembling the transcriptome, it is becoming clear that the mammal genome is pervasively tran- scribed, and large numbers of long noncodi...
关键词:RNA One Novel Long Noncoding RNA lnc10 in Drosophila RACE PCR length body ORF 
Current Advances in Epigenetic Modification and Alteration during Mammalian Ovarian Folliculogenesis被引量:4
《Journal of Genetics and Genomics》2012年第3期111-123,共13页Zengxiang Pan Jinbi Zhang Qifa Li Yinxia Li Fangxiong Shi Zhuang Xie Honglin Liu 
supported by the Chinese National Natural Science Foundation (No.30901027);the National Key Scientific Program (No.2007CB947403);funded,in part,by the grants for the Doctoral Program of Higher Education of China (No.20090097120043);the Fundamental Research Funds for the Central Universities(No.Y0201100257)
During the growth and development of mammalian ovarian follicles, the activation and deactivation of mass genes are under the synergistic control of diverse modifiers through genetic and epigenetic events. Many factor...
关键词:EPIGENETICS DNA methylation Histone modification Noncoding RNAs OVARY FOLLICULOGENESIS 
Reversibility and heritability of liver fibrosis:Implications for research and therapy被引量:24
《World Journal of Gastroenterology》2015年第17期5138-5148,共11页Hussein M Atta 
Egyptian Science and Technology Development Fund under Project 1550
Liver fibrosis continues to be a major health problem worldwide due to lack of effective therapy.If the etiology cannot be eliminated,liver fibrosis progresses to cirrhosis and eventually to liver failure or malignanc...
关键词:EPIGENETICS Epimutations Inheritance LIVERCIRRHOSIS Hepatic stellate cells HISTONE modification DNA methylation MicroRNA Long noncoding RNA Transcription regulation 
LINC00511 promotes gastric cancer cell growth by acting as a ceRNA被引量:10
《World Journal of Gastrointestinal Oncology》2020年第4期394-404,共11页Chong-Bing Sun Hong-Yi Wang Xiao-Qing Han Yong-Ning Liu Meng-Chun Wang Hong-Xia Zhang You-Feng Gu Xiao-Gang Leng 
BACKGROUND Gastric cancer(GC)is one of the most aggressive malignancies,with a high incidence and poor prognosis worldwide.Recently,accumulating evidence has illustrated that long noncoding RNAs(lnc RNAs)play pivotal ...
关键词:LINC00511 miR-124-3p PDK4 LONG noncoding RNAS GASTRIC cancer 
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