DOPAMINE

作品数:528被引量:879H指数:11
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相关领域:医药卫生更多>>
相关作者:王俊姜宏谢俊霞邱海波杨毅更多>>
相关机构:首都医科大学北京大学中国科学院山东大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Adeno-associated viral vectors for modeling Parkinson's disease in non-human primates
《Neural Regeneration Research》2026年第1期224-232,共9页Julia Chocarro JoséL.Lanciego 
supported by grants PID2020-120308RB-I00 and PID2023-147802OB-I00 funded by MICIU/AEI/10.13039/501100011033;FEDER,UE,by Aligning Science Across Parkinson’s(ref.ASAP-020505)through the Michael J.Fox Foundation for Parkinson’s Research;by CiberNed Intramural Collaborative Projects(ref.PI2020/09);by the Spanish Fundación Mutua Madrile?a de Investigación Médica(to JLL)。
The development of clinical candidates that modify the natural progression of sporadic Parkinson's disease and related synucleinopathies is a praiseworthy endeavor,but extremely challenging.Therapeutic candidates that...
关键词:adeno-associated viral vectors ALPHA-SYNUCLEIN DOPAMINE Lewy bodies NEURODEGENERATION NEUROMELANIN NEUROPATHOLOGY substantia nigra 
Context-dependency in medicine:how neuronal excitability influences the impact of dopamine on cognition
《Neural Regeneration Research》2025年第11期3225-3226,共2页Mahboubeh Ahmadi Nahid Rouhi Javad Mirnajafi-Zadeh Bechara J.Saab 
Dopamine,often termed the"feel-good"neurotransmitter,plays a crucial role in myriad physiological and psychological brain processes.While dopamine is primarily associated with pleasure,reward,and motivation,its effect...
关键词:DOPAMINE EPILEPSY primarily 
Challenges in using virtual reality technology for pain relief
《World Journal of Clinical Cases》2025年第16期76-79,共4页Takahiko Nagamine 
The present paper addresses two issues pertaining to the use of virtual reality(VR).One issue pertains to the equipment utilized.VR technology can be classified into two main categories:Immersive and non-immersive.The...
关键词:Virtual reality Acute pain Chronic pain Brain network:Medial prefrontal cortex DOPAMINE 
How dopamine tunes parvalbumin interneurons in the hippocampus:new experimental observations in Alzheimer's disease
《Neural Regeneration Research》2025年第5期1405-1406,共2页Livia La Barbera Paraskevi Krashia Annalisa Nobili 
supported by an under-40 grant from the Italian Association for Alzheimer’s Research [AIRALZH AGYR2021];the Strategic University Projects–Young Researcher Independence grant [YRG2021] from the Università Campus Bio-Medico di Roma (Rome, Italy)(to LLB);Italian Ministry of Health [Research Grant:GR-2019-12370446];the American Alzheimer’s Association [AARG-22-922961](to PK)。
Despite decades of dedicated resea rch,Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disorder for which the mechanisms of onset are sti unc ear.AD is cha racterized by featured histologi...
关键词:ALZHEIMER alterations DOPAMINE 
Progressive noradrenergic degeneration and motor cortical dysfunction in Parkinson’s disease
《Acta Pharmacologica Sinica》2025年第4期829-835,共7页Wei Zhou Hong-Yuan Chu 
funded in part by Aligning Science Across Parkinson’s(ASAP-020572);NIH grants(R01NS121371 and R21NS135545);Department of Defense Congressionally Directed Medical Research Programs(W81XWH-21-1-0943);Parkinson’s Foundation(PF-IMP-1045313).
The locus coeruleus norepinephrine(LC-NE)system plays an important role in regulating brain function,and its neuronal loss has been well-documented in Parkinson’s disease(PD).The LC-NE neurodegeneration is believed t...
关键词:locus coeruleus NOREPINEPHRINE DOPAMINE parkinson’s disease motor cortex cognition 
Restless head syndrome:A retrospective study
《World Journal of Methodology》2025年第1期51-59,共9页Sanjay Prakash Varoon Vadodaria Niraj Chawda Chetsi S Shah Anurag Prakash 
BACKGROUND Restless legs syndrome(RLS)is characterized by an urge to move with an unpleasant sensation in the lower limbs.RLS typically affects the legs.However,it can also affect several other body regions,such as th...
关键词:Restless legs syndrome Restless head syndrome DOPAMINE HEADACHE MIGRAINE Tension-type headache 
Additive neurorestorative effects of exercise and docosahexaenoic acid intake in a mouse model of Parkinson’s disease
《Neural Regeneration Research》2025年第2期574-586,共13页Olivier Kerdiles Méryl-Farelle Oye Mintsa Mi-mba Katherine Coulombe Cyntia Tremblay VincentÉmond Martine Saint-Pierre Clémence Rouxel Line Berthiaume Pierre Julien Francesca Cicchetti Frédéric Calon 
supported by funding from Parkinson Canada;funded by a scholarship from Parkinson Canada;a scholarship from Fonds d’Enseignement et de Recherche (FER) (Faculty of Pharmacy, Université Laval)
There is a need to develop interventions to slow or reverse the degeneration of dopamine neurons in Parkinson’s disease after diagnosis.Given that preclinical and clinical studies suggest benefits of dietary n-3 poly...
关键词:6-HYDROXYDOPAMINE DOPAMINE dopamine transporter EXERCISE neurorestoration Parkinson’s disease polyunsaturated fatty acids omega-3 
Astrocytic G Protein-Coupled Receptors in Drug Addiction
《Engineering》2025年第1期256-265,共10页Alexander K.Zinsmaier Eric J.Nestler Yan Dong 
partially supported by the National Institutes of Health(NIH)grants DA056213(to Alexander K.Zinsmaier),DA053388(to Eric J.Nestler),DA023206(to Yan Dong),DA060868(to Yan Dong),and DA040620(to Eric J.Nestler and Yan Dong)。
Understanding the cellular mechanisms of drug addiction remains a key task in current brain research.While neuron-based mechanisms have been extensively explored over the past three decades,recent evidence indicates a...
关键词:ASTROCYTE GPCR Nucleus accumbens ADDICTION MGLUR5 DOPAMINE 
Light-controlled crosslinked multifunctional "Band-Aids" as dual-stage wound dressing for dynamic wound closure
《Collagen and Leather》2024年第4期123-140,共18页Xinyue Zhang Xue Zhan Chen Hu Zuqin Dong Tao Luo Haihang Li Xiaoju Fan Jie Liang Yafang Chen Yujiang Fan 
supported by National Key R&D Program of China(Grant No.2022YFC2401800);National Natural Science Foundation of China(Grant No.32301116);Sichuan Science and Technology Program(Grant No.2023NSFSC0996)
The objective of regenerative wound healing dressings is to accelerate skin tissue regeneration and restore normal physiological function at wound sites.Achieving this goal requires biomaterials capable of repairing d...
关键词:Dual-stage wound dressing system Recombinant humanized typeⅢcollagen DOPAMINE Lightcontrolled crosslinked Hemostatic property 
Acute Recruitment of VTA Dopamine Neurons by mPOA Esr1+Neurons to Facilitate Consummatory Male Mating Actions
《Neuroscience Bulletin》2024年第11期1745-1750,共6页Zhuo-Lei Jiao Min Zhang Ya-Nan Wu Shuai-Shuai Li Meng-Tong Gao Wen Zhang Xiao-Hong Xu 
supported by grants from STI 2030-Major Projects(2021ZD0203203,2021ZD02044400);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32000000);the National Natural Science Foundation of China(31871066,31922028,and 31900721);the Shanghai Municipal Science and Technology Major Project(2018 SHZDZX05).
Dear Editor,Instinctual male mating actions serve the fundamental purpose of bringing the two gametes together in sexually reproducing species[1,2].Upon encountering a conspecific female,a male mouse investigates the ...
关键词:MOUNT DOPAMINE bringing 
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