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Scavenger Receptor Class B type 1(SR-B1)and the modifiable risk factors of stroke
《Chinese Neurosurgical Journal》2020年第1期35-44,共10页Lenahan Cameron Huang Lei Travis Zachary D. Zhang John H. 
Stroke is a devastating disease that occurs when a blood vessel in the brain is either blocked or ruptured,consequently leading to deficits in neurological function.Stroke consistently ranked as one of the top causes ...
关键词：Scavenger Receptor Class B type 1 SR-B1 ATHEROSCLEROSIS Coronary heart disease Diabetes mellitus Sickle cell OBESITY Physical inactivity HYPERCHOLESTEROLEMIA Hypertension 
Non-alcoholic fatty liver disease and metabolic syndrome in obese children
《World Journal of Gastroenterology》2011年第39期4445-4446,共2页Mehmet Emre Atabek 
I read with great interest the article of Fu et al who investigated whether non-alcoholic fatty liver disease(NAFLD)is an early mediator for prediction of metabolic syndrome,and whether liver B-ultrasound could be use...
关键词：Non-alcoholic fatty liver disease Metabolic syndrome Obese children 
Progression of motor symptoms in Parkinson’s disease被引量：6
《Neuroscience Bulletin》2012年第1期39-48,共10页Ruiping Xia Zhi-Hong Mao 
supported by the National Institutes of Health (R15-HD061022 and R15-HD061022-S1);the Faculty Development Fund of the School of Pharmacy and Health Professions,Creighton University in Omaha Nebraska,USA
Parkinson＇s disease （PD） is a chronic progressive neurodegenerative disease that is clinically manifested by a triad of cardinal motor symptoms - rigidity, bradykinesia and tremor - due to loss of dopaminergic neur...
关键词：Parkinson＇s disease PROGRESSION motor symptoms disease modification TREATMENT 
Treatment of recurrent sigmoid volvulus in Parkinson's disease by percutaneous endoscopic colostomy被引量：1
《World Journal of Gastroenterology》2012年第40期5812-5815,共4页Susan Toebosch Vera Tudyka Ad Masclee Ger Koek 
The exact aetiology of sigmoid volvulus in Parkinson's disease(PD) remains unclear.A multiplicity of factors may give rise to decreased gastrointestinal function in PD patients.Early recognition and treatment of const...
关键词：Colonic dysfunction COLOSTOMY Endoscopictreatment Parkinson＇s disease Sigmoid volvulus 
Use of secondary preventive medications in patients with atherosclerotic disease in urban China： a cross-sectional study of 16 860 patients被引量：10
《Chinese Medical Journal》2012年第24期4361-4367,共7页LI Jing CHEN Yi-ping LI Xi Jane Armitage FENG Fang LIU Jia-min GAO Yan ZHANG Hai-bo ZHANG Dan HUNDEI Wuhan-bilige CHEN Zheng-ming CHEN Fang Jemma C Hopewell Elsa Valdes-Marquez Martin Landray JIANG Li-xin 
Background Despite considerable improvements in the care of patients with cardiovascular disease in various populations over the last few decades, there are still limited data about long-term treatment patterns among ...
关键词：coronary heart disease ischaemic stroke STATIN secondary prevention 
阿尔茨海默病的扩瞳试验研究被引量：6
《中华精神科杂志》2001年第1期1-4,共4页项志清 陈月敏 颜文伟 
目的　验证扩瞳试验能否用于诊断阿尔茨海默病 (AD)。方法　用非接触型双侧瞳孔红外同步记录分析仪对滴入 0 0 1%托吡卡胺后的瞳孔变化进行测定 ,并自动分析瞳孔直径扩大 (按对照侧校正 )的百分比。共测定AD患者 5 2例、血管性痴呆 (VD...
关键词：ALZHEIMER DISEASE 瞳孔反射 血管性痴呆 精神分裂症 老年性痴呆 扩瞳试验 
LRRK2G2019S Mutation Inhibits Degradation of α-Synuclein in an In Vitro Model of Parkinson's Disease被引量：1
《Current Medical Science》2018年第6期1012-1017,共6页Dan HU Jian-yi NIU Jing XIONG Shu-ke NIE Fei ZENG Zhao-hui ZHANG 
the National Natura Science Foundation of China(NSFC)(No.81401051,No 81671051,and No.81501107).
The G2019S mutation of the leucine-rich repeat kinase 2(LRRK2)is the most common genetic cause of Parkinson's disease (PD).However,the molecular mechanisms of LRRK2 mutation contributing to the onset and progression o...
关键词：Α-SYNUCLEIN leucine-rich REPEAT KINASE 2 Parkinson's disease LYSOSOME 
20C, a bibenzyl compound isolated from Gastrodia elata, protects PC12 cells against rotenone-induced apoptosis via activation of the Nrf2/ARE/HO-1 signaling pathway被引量：16
《Acta Pharmacologica Sinica》2016年第6期731-740,共10页Ju-yang HUANG Yu-he YUAN Jia-qing YAN Ya-nan WANG Shi-feng CHU Cheng-gen ZHU Qing-lan GUO Jian-gong SHI Nai-hong CHEN 
Aim： Our preliminary study shows that a bibenzyl compound isolated from Gastrodia elata, 2-[4-hydroxy-3-（4-hydroxybenzyl）benzyl]-4-（4-hydroxybenzyl）phenol （designated 20C）, protects PC12 cells against H202-indu...
关键词：bibenzyl compound Gastrodia elata ROTENONE apoptosis oxidative stress Nrf2 NEUROPROTECTION Parkinson＇s disease PC12 cells 
Echinacoside Protects Against MPP+-Induced Neuronal Apoptosis via ROS/ATF3/CHOP Pathway Regulation被引量：19
《Neuroscience Bulletin》2016年第4期349-362,共14页Qing Zhao Xiaoyan Yang Dingfang Cai Ling Ye Yuqing Hou Lijun Zhang Jiwei Cheng Yuan Shen Kaizhe Wang Yu Bai 
supported by the National Natural Science Foundation of China(81202814);the Shanghai Municipal Commission of Health and Family Planning(20124y116);the Young Teachers Training Funding Scheme of Shanghai Colleges and Universities,China(zzszy12026)
Echinacoside （ECH） is protective in a mouse model of Parkinson＇ s disease （PD） induced by 1-methyl-4- phenylpyridinium ion （MPP＋）. To investigate the mechanisms involved, SH-SYSY neuroblastoma ceils were treat...
关键词：ECHINACOSIDE Parkinson＇s disease 1-Methyl-4-phenylpyridinium ion. Reactive oxygen species ATF3 CHOP 
Autoantibodies in Alzheimer's disease:potential biomarkers,pathogenic roles,and therapeutic implications被引量：1
《The Journal of Biomedical Research》2016年第5期361-372,共12页Jianming Wu Ling Li 
supported in part by grants from the National Institute of Health(HL117652)(to JW);the Academic Health Center(Faculty Research Development Program) of the University of Minnesota (to LL and JW)
Alzheimer＇s disease （AD） is a prevalent and debilitating neurodegenerative disorder in the elderly. The etiology of AD has not been fully defined and currently there is no cure for this devastating disease. Compell...
关键词：Alzheimer＇s disease AUTOIMMUNE AUTOANTIBODY biomarker pathogenesis immunotherapy 
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