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SPECTROMETRY: 作品数：461被引量：896H指数：12; 导出分析报告; 相关领域：理学生物学更多>>; 相关作者：姜山何明武绍勇石磊李世红更多>>; 相关机构：中国计量科学研究院中国原子能科学研究院吉林大学广西大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家质检总局科技计划项目国家教育部博士点基金更多>>

Review of the diagnosis of gastrointestinal lanthanum deposition被引量：6: 《World Journal of Gastroenterology》2020年第13期1439-1449,共11页Masaya Iwamuro Haruo Urata Takehiro Tanaka Hiroyuki Okada; Lanthanum carbonate is used for treatment of hyperphosphatemia mostly in patients with chronic renal failure.Although lanthanum carbonate is safe,recently,lanthanum deposition in the gastrointestinal mucosa of patient...; 关键词：LANTHANUM CARBONATE HYPERPHOSPHATEMIA GASTROINTESTINAL endoscopy LANTHANUM phosphate Scanning electron microscopy Energy-dispersive X-ray SPECTROMETRY

Mitochondrial metabolomic profiling for elucidating the alleviating potential of Polygonatum kingianum against high-fat diet-induced nonalcoholic fatty liver disease被引量：8: 《World Journal of Gastroenterology》2019年第43期6404-6415,共12页Xing-Xin Yang Jia-Di Wei Jian-Kang Mu Xin Liu Feng-Jiao Li Yan-Qin Li Wen Gu Jing-Ping Li Jie Yu; the National Natural Science Foundation of China,No.81660596;the National Natural Science Foundation of China,No.81760733;the Science and Technology Project of Yunnan China,No.2017FF117-013;the Science and Technology Project of Yunnan China,No.2016FD050;the Application and Basis Research Project of Yunnan China,No.201801CH00227; BACKGROUND Developing mitochondrial regulators/nutrients from natural products to remedy mitochondrial dysfunction represent attractive strategies for therapy of nonalcoholic fatty liver disease(NAFLD).Polygonatum kin...; 关键词：Metabolomics MITOCHONDRIA Multivariate statistical analysis Non-alcoholic FATTY liver POLYGONATUM kingianum Ultra-high performance liquid chromatography/mass SPECTROMETRY

Δ4-3-oxosteroid-5β-reductase deficiency: Responses to oral bile acid therapy and long-term outcomes被引量：7: 《World Journal of Gastroenterology》2019年第7期859-869,共11页Mei-Hong Zhang Kenneth DR Setchell Jing Zhao Jing-Yu Gong Yi Lu Jian-She Wang; Supported by the National Natural Science Foundation of China,No.81570468 and No.81741056;Jinshan Science and Technology Commission,No.2014-3-07; BACKGROUND Disorders of primary bile acid synthesis may be life-threatening if undiagnosed,or not treated with primary bile acid replacement therapy. To date, there are few reports on the management and follow-up of p...; 关键词：Δ4-3-oxosteroid-5β-reductase DEFICIENCY Mass SPECTROMETRY BILE ACID synthesis DISORDER Chenodeoxycholic ACID Ursodeoxycholic ACID

Dynamic changes of key metabolites during liver fibrosis in rats被引量：3: 《World Journal of Gastroenterology》2019年第8期941-954,共14页Jiong Yu Jian-Qin He De-Ying Chen Qiao-Ling Pan Jin-Feng Yang Hong-Cui Cao Lan-Juan Li; Supported by the Stem Cell and Translational Research,the National Key Research and Development Program of China,No.2016YFA0101001;Independent Project Fund of the State Key Laboratory for Diagnosis and Treatment of Infectious Disease(SKL DTID); BACKGROUND Fibrosis is the single most important predictor of significant morbidity and mortality in patients with chronic liver disease.Established non-invasive tests for monitoring fibrosis are lacking,and new bioma...; 关键词：Ultra-performance liquid chromatography-mass SPECTROMETRY METABONOMICS Liver FIBROSIS Biomarker Cervonoyl ethanolamide β-muricholic acid

Integrated metabolomic profiling for analysis of antilipidemic effects of Polygonatum kingianum extract on dyslipidemia in rats被引量：10: 《World Journal of Gastroenterology》2018年第48期5505-5524,共20页Xing-Xin Yang Jia-Di Wei Jian-Kang Mu Xin Liu Jin-Cai Dong Lin-Xi Zeng Wen Gu Jing-Ping Li Jie Yu; Supported by the National Natural Science Foundation of China,No.81660596 and No.81760733;the Application and Basis Research Project of Yunnan,China,No.2016FD050 and No.2017FF117-013;the Fund for Young and Middle-aged Academic and Technological Leaders of Yunnan,No.2015HB053; AIM To identify the effects and mechanism of action of Polygonatum kingianum(P. kingianum) on dyslipidemia in rats using an integrated untargeted metabolomic method.METHODS A rat model of dyslipidemia was induced with...; 关键词：DYSLIPIDEMIA LIPID regulation Metabolomics Multivariate statistical ANALYSIS POLYGONATUM kingianum Ultra-high performance liquid chromatography/mass SPECTROMETRY

Metabolomic alterations and chromosomal instability status in gastric cancer被引量：8: 《World Journal of Gastroenterology》2018年第33期3760-3769,共10页Cheng-Kun Tsai Ta-Sen Yeh Ren-Chin Wu Ying-Chieh Lai Meng-Han Chiang Kuan-Ying Lu Cheng-Yu Hung Hung-Yao Ho Mei-Ling Cheng Gigin Lin; Supported by the Ministry of Science and Technology Taiwan grant,No.MOST 106-2314-B-182A-019-MY3;the Chang Gung Foundation,No.CMRPG3E1321-2,No.IRB201601916B0,and No.IRB103-7448B; AIM To explore the correlation of metabolomics profiles ofgastric cancer(GC) with its chromosomal instability(CIN) status.METHODS Nineteen GC patients were classified as CIN and nonCIN type by The Cancer Genome Atlas ...; 关键词：GASTRIC cancer Metabolomics ONCOGENE COPY-NUMBER CHROMOSOMAL instability Liquid chromatography-mass SPECTROMETRY

Recent advances in mass spectrometry-based proteomics of gastric cancer被引量：9: 《World Journal of Gastroenterology》2016年第37期8283-8293,共11页Changwon Kang Yejin Lee J Eugene Lee; Supported by the National Research Council of Science and Technology,No.DRC-14-2-KRISS;the National Research Foundation of Korea,No.2013056334,No.2014044403 and No.2015052849; The last decade has witnessed remarkable technological advances in mass spectrometry-based proteomics. The development of proteomics techniques has enabled the reliable analysis of complex proteomes, leading to the id...; 关键词：GASTRIC cancer Mass SPECTROMETRY PROTEIN identification PROTEOMICS PROTEIN quantification

Insights into glycan biosynthesis in chemically-induced hepatocellular carcinoma in rats: A glycomic analysis: 《World Journal of Gastroenterology》2015年第20期6167-6179,共13页Amr Amin Asma Bashir Nazar Zaki Diane McCarthy Sanjida Ahmed Mohamed Lotfy; Supported by National Research Foundation Grant No.UIRCA 2012-21832 for A.Amin; AIM： To evaluate the qualitative and quantitativechanges in N-linked glycosylation, which occurredin association with diethyl nitrosamine-inducedhepatocellular carcinoma （HCC） in rodents.METHODS： Liver tissues of ...; 关键词：Matrix-assisted laser desorption/ionizationtime-of-flight mass SPECTROMETRY Hepatocellularcarcinoma GLYCOMICS Biosynthetic pathways

Mechanisms of trichostatin A inhibiting AGS proliferation and identification of lysine-acetylated proteins被引量：1: 《World Journal of Gastroenterology》2013年第21期3226-3240,共15页Yu-Gang Wang Na Wang Guang-Ming Li Wen-Li Fang Jue Wei Jia-Li Ma Ting Wang Min Shi; Supported by Shanghai Municipal Health Bureau Key Disciplines Grant, No. ZK2012A05;National Natural Science Foundation, No. 81070344; AIM: To explore the effect of lysine acetylation in related proteins on regulation of the proliferation of gastric cancer cells, and determine the lysine-acetylated proteins and the acetylated modified sites in AGS ga...; 关键词：TRICHOSTATIN A ACETYLATION modification GASTRIC cancer Mass SPECTROMETRY ATP5O PKM2

Human liver tissue metabolic profiling research on hepatitis B virus-related hepatocellular carcinoma被引量：6: 《World Journal of Gastroenterology》2013年第22期3423-3432,共10页Shu-Ye Liu Rikki-Lei Zhang Hua Kang Zhi-Juan Fan Zhi Du; AIM: To select characteristic endogenous metabolites in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients and to identify their molecular mechanism and potential clinical value. METHODS: An ultra...; 关键词：HEPATOCELLULAR CARCINOMA Metabolomics Characteristic METABOLITES Potential BIOMARKER Ultra performance liquid chromatography-mass SPECTROMETRY

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