ANTI-INFLAMMATORY

作品数：629被引量：1827H指数：19
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What is the pathophysiology of inflammation-induced cortical injury in the perinatal brain?
《Neural Regeneration Research》2026年第2期502-505,共4页Sharmony B.Kelly Alistair J.Gunn Rodney W.Hunt Robert Galinsky 
supported by National Health and Medical Research Council of Australia(APP1090890 and APP1164954);Cerebral Palsy Alliance(ERG02123);the Victorian Government’s Operational Infrastructure Support Program。
Perinatal exposure to infection/inflammation is highly associated with neural injury,and subsequent impaired cortical growth,disturbances in neuronal connectivity,and impaired neurodevelopment.However,our understandin...
关键词：anti-inflammatory therapies cerebral cortex CHORIOAMNIONITIS ELECTROENCEPHALOGRAPHY magnetic resonance imaging neonatal sepsis NEURODEVELOPMENT NEUROINFLAMMATION neurons 
Taurine: a promising nutraceutic in the prevention of retinal degeneration被引量：2
《Neural Regeneration Research》2024年第3期606-610,共5页Diego García-Ayuso Johnny Di Pierdomenico Ana Martínez-Vacas Manuel Vidal-Sanz Serge Picaud María PVillegas-Pérez 
supported by Instituto de Salud CarlosⅢ(ISCⅢ):PI19/00203;cofunded by ERDF;"A way to make Europe"to MPVP and DGA;P122/00900;RD16/0008/0026 co-funded by ERDF;"A way to make Europe"to MPVP and RD21/0002/0014;financiado porla Unión Europea-NextGenerationEU;Fundación Robles Chillida to DGA;RED2018-102499-T;PID201 9-106498GB-I00;funded by MCIN/AEI/10.13039/501100011 033 to MVS;IHU FOReSIGHT[ANR-18-IAHU-0001] to SP
Taurine is considered a non-essential amino acid because it is synthesized by most mammals.However,dietary intake of taurine may be necessary to achieve the physiological levels required for the development,maintenanc...
关键词：amino acid ANTI-INFLAMMATORY ANTIOXIDANT gamma-aminobutyric acid NUTRACEUTICAL photoreceptor degeneration RETINA retinitis pigmentosa TAURINE 
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis被引量：2
《Neural Regeneration Research》2024年第3期671-679,共9页Chunyun Liu Shangde Guo Rong Liu Minfang Guo Qing Wang Zhi Chai Baoguo Xiao Cungen Ma 
supported by a grant from the Department of Science and Technology of Shanxi Province,China,No.20210302123477(to CL);Datong Bureau of Science and Technology of China,No.2020152(to CL);the Opening Foundation of Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine,No.2022-KF-03(to CL).
Multiple sclerosis is characterized by demyelination and neuronal loss caused by inflammatory cell activation and infiltration into the central nervous system.Macrophage polarization plays an important role in the pat...
关键词：ANTI-INFLAMMATORY experimental autoimmune encephalomyelitis FASUDIL macrophage multiple sclerosis PRO-INFLAMMATORY Rho kinase 
Biomaterials-based anti-inflammatory treatment strategies for Alzheimer's disease被引量：1
《Neural Regeneration Research》2024年第1期100-115,共16页Jianjian Chu Weicong Zhang Yan Liu Baofeng Gong Wenbo Ji Tong Yin Chao Gao Danqi Liangwen Mengqi Hao Cuimin Chen Jianhua Zhuang Jie Gao You Yin 
supported by the National Natural Science Foundation of China,Nos.82072051 and 81771964(both to JG);the Natural Science Foundation of Shanghai Municipal Science and Technology Commission,No.22ZR147750(to YY);Science and Technology Support Projects in Biomedicine Field of Shanghai Science and Technology Commission,No.19441907500(to YY);Innovative Clinical Research Project of Changzheng Hospital,No.2020 YLCYJ-Y02(to YY);Characteristic Medical Service Project for the Army of Changzheng Hospital,No.2020 CZWJFW12(to YY)。
The current therapeutic drugs for Alzheimer's disease only improve symptoms,they do not delay disease progression.Therefo re,there is an urgent need for new effective drugs.The underlying pathogenic factors of Alzheim...
关键词：Alzheimer's disease ANTI-INFLAMMATION blood-brain barrier drug delivery MICROGLIA NANOPARTICLES NEUROINFLAMMATION plant extracts 
Neuroprotective effects of meloxicam on transient brain ischemia in rats:the two faces of anti-inflammatory treatments被引量：4
《Neural Regeneration Research》2023年第9期1961-1967,共7页Irene Fernández Ugidos Paloma González-Rodríguez María Santos-Galdiano Enrique Font-Belmonte Berta Anuncibay-Soto Diego Pérez-Rodríguez JoséManuel Gonzalo-Orden Arsenio Fernández-López 
supported by MINECO and FEDER funds:ref CPP2021-008855 and RTC-2015-4094-1,Junta de Castilla y León ref.LE025P1 7;Neural Therapies SL;ref.NTDev-01 (all to AFL and JMGO)。
The inflammato ry response plays an important role in neuroprotection and regeneration after ischemic insult.The use of non-ste roidal anti-inflammatory drugs has been a matter of debate as to whether they have benefi...
关键词：ANTI-INFLAMMATORIES ASTROCYTE axonal sprouting cylinder test DOUBLECORTIN focal brain ischemia glial scar inflammation neuroprotection new neuron generation transient stroke 
Spliceosomal GTPase Eftud2 regulates microglial activation and polarization被引量：3
《Neural Regeneration Research》2023年第4期856-862,共7页Guo-Chao Yang Yuan Shi Chao-Nan Fan Ying Li Meng-Qi Yuan Jie Pei Yan Wu Hai-Tao Wu 
supported by the National Natural Science Foundation of China,Nos.32171148,31770929,31522029(all to HTW);the National Key Research and Development Program of China,Nos.2021ZD0202500,2021YFA1101801(both to HTW);a grant from Beijing Commission of Science and Technology of China,Nos.Z181100001518001,Z161100000216154(both to HTW)。
Elongation factor Tu GTP binding domain protein 2(Eftud2)is a spliceosomal GTPase that serves as an innate immune modulator restricting virus infection.Microglia are the resident innate immune cells and the key player...
关键词：Alzheimer’s disease anti-inflammatory phenotype BV2 Eftud2 inflammation LIPOPOLYSACCHARIDE MICROGLIA nuclear factor-kappaB proinflammatory phenotype spliceosomal GTPase 
Lycium barbarum extract promotes M2 polarization and reduces oligomeric amyloid-β-induced inflammatory reactions in microglial cells被引量：5
《Neural Regeneration Research》2022年第1期203-209,共7页Zhong-Qing Sun Jin-Feng Liu Wei Luo Ching-Hin Wong Kwok-Fai So Yong Hu Kin Chiu 
supported by Midstream Research Program for Universities;Hong Kong Special Administrative Region,China,No.MRP-092-17X。
Lycium barbarum(LB)is a traditional Chinese medicine that has been demonstrated to exhibit a wide variety of biological functions,such as antioxidation,neuroprotection,and immune modulation.One of the main mechanisms ...
关键词：Alzheimer’s disease amyloid-β anti-inflammatory factors Lycium barbarum extract M1 microglia M2 microglia NEUROINFLAMMATION proinflammatory factors 
Potential therapeutic effects of polyphenols in Parkinson's disease:in vivo and in vitro pre-clinical studies被引量：2
《Neural Regeneration Research》2021年第2期234-241,共8页Claudio Giuliano Silvia Cerri Fabio Blandini 
Parkinson's disease is a neurodegenerative disorder characterized by a combination of severe motor and non-motor symptoms.Over the years,several factors have been discovered to play a role in the pathogenesis of this ...
关键词：ALPHA-SYNUCLEIN ANTI-INFLAMMATORY ANTIOXIDANTS natural molecules NEUROPROTECTION Parkinson's disease POLYPHENOLS syntomatic effect 
Combining anti-inflammatory and unfolding protein responses to fight stroke被引量：1
《Neural Regeneration Research》2019年第3期450-451,共2页Berta Anuncibay-Soto Enrique Font-Belmonte Arsenio Fernández-López 
This work was supported by the Spanish Ministerio de Economia y Competitividad(MINECO);co-financed with FEDER funds ‘‘una manera de hacer Europa"(reference RTC-2015-4094-1);Junta de Castilla y León(reference LE025P17);Neural Therapies SL(reference NT-Dev01)
This perspective shows an attempt to obtain synergy effects to fight ischemic stroke by combining agents acting on two different homeostatic mechanisms:inflammation and unfolded protein response (Anuncibay-Soto et al....
关键词：COMBINING ANTI-INFLAMMATORY 
Melatonin for the treatment of spinal cord injury被引量：5
《Neural Regeneration Research》2018年第10期1685-1692,共8页Yan Zhang Wen-Xiu Zhang Yan-Jun Zhang Ya-Dong Liu Zong-Jian Liu Qi-Chao Wu Yun Guan Xue-Ming Chen 
supported by the National Natural Science Foundation of China,No.81671161(to ZJL)
Spinal cord injury（SCI） from trauma or disease severely impairs sensory and motor function. Neurorehabilitation after SCI is a complex medical process that focuses on improving neurologic function and repairing dama...
关键词：spinal cord injury melatonin secondary damage NEUROPROTECTION antioxidative antiapoptotic ANTI-INFLAMMATORY synergistic effects neural regeneration 
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