SYNAPTOSOMES

作品数:12被引量:12H指数:3
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相关领域:医药卫生更多>>
相关作者:李勇江冬英王影杨祥良颜景芝更多>>
相关机构:华中科技大学大连医科大学徐州医学院更多>>
相关期刊:《Acta Pharmacologica Sinica》《Science Bulletin》《Progress in Natural Science:Materials International》《Journal of Traditional Chinese Medicine》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划江苏省教育厅科研基金更多>>
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On the road towards the global analysis of human synapses
《Neural Regeneration Research》2017年第10期1586-1589,共4页G.Aleph Prieto Carl W.Cotman 
supported by National Institutes of Health Grants R21-AG048506,P01-AG000538 and RO1-AG34667(to CWC);UC MEXUS-CONACYT Grant CN-16-170(to GAP and CWC)
Synapses are essential units for the flow of information in the brain.Over the last 70 years,synapses have been widely studied in multiple animal models including worms,fruit flies,and rodents.In comparison,the study ...
关键词:fluorescence analysis of single-synapse long-term potentiation array tomography positron emission tomography synaptosomes flow cytometry microscopy [11C]UCB-J[(R)-1-((3-(11C-methyl-11C)pyridin-4-yl)methyl)-4-(3 4 5-trifluorophenyl)pyrrolidin-2-one] 
Age related interaction of dopamine and serotonin synthesis in striatal synaptosomes
《BIOCELL》2013年第2期17-21,共5页MANOOCHEHR MESSRIPOUR AZADEH MESRIPOUR 
supported by the Research Council of Khorasgan Branch,Islamic Azad University,Isfahan.
Tyrosine hydroxylase and tryptophan hydroxylase are key rate limiting enzymes in the biosynthesis of dopamine and serotonin,respectively.Since both enzymes are active in striatum,and affected by age,this study was und...
关键词:aging nerve ENDING NEUROTRANSMITTER TYROSINE HYDROXYLASE TRYPTOPHAN HYDROXYLASE 
HDT-1, a new synthetic compound, inhibits glutamate release in rat cerebral cortex nerve terminals (synaptosomes)
《Acta Pharmacologica Sinica》2008年第11期1289-1295,共7页Su-jane WANG Shiu-huey CHOU Yuh-chi KUO Shang-shing Peter CHOU Woan-fang TZENG Jxh-yih LEU Rwei-fen S HUANG Yih-fong LIEW 
Aim: Excessive glutamate release has been proposed to be involved in the pathogenesis of several neurological diseases. In this study, we investigated the effect of HDT-1 (3, 4, 4a, 5, 8, 8a-hexahydro-6,7-dimethyl-...
关键词:isoquinoline alkaloid NEUROPROTECTION glutamate release voltage-dependent Ca^2+ channel SYNAPTOSOME cerebral cortex 
Inhibition of botulinum toxin's association with rat brain synaptosomes by toosendanin,an antibotulismic triterpenoid被引量:3
《Neural Regeneration Research》2006年第6期489-492,共4页Jianying Zhou Yuliang Shi 
the Major State Basic Research Development Program of China (973 pro-gram), No. G1999054000; the National Natural Science Foun-dation of China, No. 30170302;Basic Research Program of Shanghai, No. 02JC14011
BACKGROUND: Toosendanin (TSN), a tnterpenoid derivative extracted from the bark of Melia toosendanin Sieb et Zucc, has been demonstrated to be an effective drug for treatment of experimental botulism. OBJECTIVE : ...
Effect of Propofol on Glutamate and γ-aminobutyric Acid Release from Rat Hippocampal Synaptosomes被引量:2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2005年第6期700-702,共3页尚游 姚尚龙 曾因明 刘红亮 曹君利 
ThisprojectwassupportedbyagrantfromtheFoundationofEducationCommissionofJiangsuProvince(No.KJS03084).
To investigate the effect of propofol on the release of glutamate and γ-aminobutyric acid (GABA) from rat hippocampal synatosomes, synaptosomes was made from hippocampus and incubated with artificial cerebrospinal ...
关键词:PROPOFOL HIPPOCAMPUS SYNAPTOSOME GLUTAMATE γ-aminobutyric acid 
Effect of Thiopental Sodium on the Release of Glutamate and γ-aminobutyric Acid from Rats Prefrontal Cortical Synaptosomes
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2004年第6期602-604,共3页刘红亮 姚尚龙 
Summary: To investigate the effect of thiopental sodium on the release of glutamate and γ-aminobutyric acid (GABA) from synaptosomes in the prefrontal cortex, synaptosomes were made, the spontaneous release and the e...
关键词:thiopentone SYNAPTOSOMES prefrontal cortex GLUTAMATE GABA 
Protective effects of scutellarin on superoxide-induced oxidative stress in rat cortical synaptosomes被引量:4
《Acta Pharmacologica Sinica》2003年第11期1113-1117,1174,共6页刘宏 杨祥良 王影 唐晓荞 江冬英 徐辉碧 
Project partly supported by the Ministry of Science and Technology of China (2001BA310A07).
AIM: To evaluate the effects of scutellarin on superoxide-induced oxidative stress in rat cortical synaptosomes. METHODS: Oxidative damage model was established by incubation with xanthine(0.3 mmol/L) and xanthine o...
关键词:SCUTELLARIN SYNAPTOSOMES MALONDIALDEHYDE membrane fluidity calcium Na^(+)-K^(+)-exchanging ATPase 
Changes and mechanisms of protein-tyrosine kinase and protein-tyrosine phosphatase activities after brain ischemia/reperfusion^1被引量:3
《Acta Pharmacologica Sinica》2000年第8期46-51,共6页裴林 李勇 颜景芝 张光毅 崔肇春 朱正美 
increase in total PTK and Src activities induced by I/R may be mediated via NR and L-type VGCC. The PTP activity did not change during I/R.To study the changes and mechanisms of protein-tyrosine kinase (PTK) and prote...
关键词:KETAMINE NIFEDIPINE protein-tyrosine kinase protein-tyrosine phosphatase HIPPOCAMPUS SYNAPTOSOMES cerebral ischemia reperfusion injury 
Rapid enhancement of high affinity glutamate uptake by glucocorticoids in rats cerebral cortex synaptosomes
《Progress in Natural Science:Materials International》1998年第6期67-74,共8页诸秉根 陈宜张 
Project supported by the National Natural Science Foundation of China (Grant No. 39330100).
The effects of glucocorticoids on the Na+-dependent, high affinity uptake of 3[H]-L-glutamate in synaptosomes from cerebral cortex of rats were investigated. Glucocorticoids, including corticosterone (B), cortices ter...
关键词:GLUCOCORTICOIDS GLUTAMATE UPTAKE G-PROTEIN synaptosomes. 
Effects of Tetrandrine and Fructose-1,6-diphosphate on the anti-anoxia in mice and in-tracellular free Ca^(2+) level of synaptosomes in rat brain
《西南师范大学学报(自然科学版)》1998年第5期92-98,共7页Tang Wei, female, 35 years old, lecturer. Tang\ Wei College of Physical Education, Southwest China Normal University, Chongqing 400715 
Braintisuesareunabletostoreoxygenandenergy,thustheycompletelyrelyontheoxygenandglucosefrombloodstreamtosuppl...
关键词:BRAIN RAT EFFECTS TETRANDRINE free Ca 
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