PARKINSONS

作品数:206被引量:376H指数:9
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相关领域:医药卫生生物学更多>>
相关作者:王宏梅王奇王奇更多>>
相关机构:辽东学院安徽医科大学广州中医药大学中山大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家高技术研究发展计划更多>>
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  • 期刊=Neural Regeneration Researchx
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Focusing on the tetra-partite synapse in Parkinson’s disease research using human patient-derived neurons
《Neural Regeneration Research》2024年第5期979-981,共3页Diogo Cordeiro Tchelet Stern Shani Stern 
supported by the Israel Science Foundation(ISF grant 1994/21 and 3252/21);Zuckerman(Zuckerman STEM leadership program)(to SS).
Parkinson’s disease(PD)was first described as a neurological disease by Dr.James Parkinson in 1817 as a“shaking palsy”.Since that time,much more is known about the pathophysiology of PD yet the disease is still unc...
关键词:patients ALZHEIMER Focus 
The dual role of necrostatin-1 in Parkinson’s disease models
《Neural Regeneration Research》2021年第10期2019-2020,共2页Eva Alegre-Cortes Guadalupe Martinez-Chacon Jose M.Fuentes Sokhna M.S.Yakhine-Diop 
This work was supported by grants from Junta de Extremadura,Spain,No.IB18048(to EAC),the ONCE Foundation(to GMC);the Isabel Gemio Foundation(to SMSYD);the Instituto de Salud Carlos III,CIBERNED,No.CB06/05/004(to JMF);partially supported by the“Fondo Europeo de Desarrollo Regional”(FEDER)from the European Union.
Neuronal cell death is the main hallmark of Parkinson’s disease(PD).It is an irreversible process promoted by neurotoxins and/or genetic mutations.Different types of cell death have been associated with PD.The mechan...
关键词:INFLAMMATION NECROSIS RUPTURE 
Retraction: Establishment of a Parkinson’s disease model in rats via striatal one-site double injection: Feasibility observation
《Neural Regeneration Research》2020年第12期2317-2317,共1页
The original article titled"Establishment of a Parkinson’s disease model in rats via striatal one-site double injection:Feasibility observation’published in Neural Regeneration Research(Liu et al.,2008a),is being re...
关键词:injection al. RATS 
Hydrogels for neuroprotection and functional rewiring: a new era for brain engineering被引量:2
《Neural Regeneration Research》2020年第5期783-789,共7页Rocío Fernández-Serra Rebeca Gallego Paloma Lozano Daniel González-Nieto 
supported by the Ministerio de Economia y Competitividad(MAT2016-79832-R,to DGN);the Community of Madrid(Neurocentro-B2017/BMD-3760,to DGN)
The neurological devastation of neurodegenerative and cerebrovascular diseases reinforces our perseverance to find advanced treatments to deal with these fatal pathologies.High-performance preclinical results have fai...
关键词:advanced therapies Alzheimer’s DISEASE biomaterials BRAIN HYDROGELS NEUROLOGICAL diseases Parkinson’s DISEASE polymers stroke 
Characteristic response of striatal astrocytes to dopamine depletion被引量:2
《Neural Regeneration Research》2020年第4期724-730,共7页Yao-Feng Zhu Wei-Ping Wang Xue-Feng Zheng Zhi Chen Tao Chen Zi-Yun Huang Lin-Ju Jia Wan-Long Lei 
supported by the National Natural Science Foundation of China,No.81471288(to WLL);the National High Technology Research and Development Program of China(863 Program),No.2017YFA0104704(to WLL)
Astrocytes and astrocyte-related proteins play important roles in maintaining normal brain function,and also regulate pathological processes in brain diseases and injury.However,the role of astrocytes in the dopamine-...
关键词:6-HYDROXYDOPAMINE ASTROCYTE dopamine depletion DOPAMINERGIC neurons Parkinson’s disease SIOOB STAT3 STRIATUM 
Ethanol extract from Gynostemma pentaphyllum ameliorates dopaminergic neuronal cell death in transgenic mice expressing mutant A53T human alpha-synuclein被引量:6
《Neural Regeneration Research》2020年第2期361-368,共8页Hyun Jin Park Ting Ting Zhao Seung Hwan Kim Chong Kil Lee Bang Yeon Hwang Kyung Eun Lee Myung Koo Lee 
supported by the National Research Foundation of Korea,grant No.2016R1D1A3B03930722(to MKL),Republic of Korea
Gynostemma(G.) pentaphyllum(Cucurbitaceae) contains various bioactive gypenosides. Ethanol extract from G. pentaphyllum(GP-EX) has been shown to have ameliorative effects on the death of dopaminergic neurons in animal...
关键词:A53T Α-SYNUCLEIN genetic mice ERK1/2 GYNOSTEMMA pentaphyllum GYPENOSIDES Parkinson’s disease retention transfer latency time 
Effect of stromal cell-derived factor-1/CXCR4 axis in neural stem cell transplantation for Parkinson’s disease被引量:4
《Neural Regeneration Research》2020年第1期112-119,共8页Jiao-Tian Xu Yuan Qian Wei Wang Xiao-Xiang Chen Yang Li Yu Li Zhi-Yong Yang Xiao-Bin Song Di Lu Xing-Li Deng 
supported by the National Natural Science Foundation of China,No.81241126(to XLD)and 81360197(to XLD);a grant from the Department of Science and Technology of Kunming Medical University in China,No.2013C227(to XLD);the Joint Special Fund for the Department of Science and Technology of Kunming Medical University in China,No.2014FB041(to XBS)
Previous studies have shown that neural stem cell transplantation has the potential to treat Parkinson’s disease,but its specific mechanism of action is still unclear.Stromal cell-derived factor-1 and its receptor,ch...
关键词:AMD3100 corpus STRIATUM CXCR4 neural stem cells Parkinson’s disease STROMAL cell-derived factor-1 substantia nigra 
Antibody-based immunotherapies for Parkinsonian syndromes
《Neural Regeneration Research》2019年第11期1903-1904,共2页Lars Tonges Maria Angela Samis Zella 
What is the rationale for immunotherapies in Parkinsonian syndromes (PS)? PS are neurodegenerative diseases which are clinically characterized by a hypokinetic phenotype in combination with additional motor and non-mo...
关键词:Parkinsonian SYNDROMES Parkinson’s disease(PD) multiple system atrophy(MSA) 
More than anti-malarial agents: therapeutic potential of artemisinins in neurodegeneration被引量:4
《Neural Regeneration Research》2019年第9期1494-1498,共5页Bing-Wen Lu Larry Baum Kwok-Fai So Kin Chiu Li-Ke Xie 
supported by the Natural Science Foundation of Beijing of China,No.7192235(to LKX)
Artemisinin,also called qinghaosu,is originally derived from the sweet wormwood plant(Artemisia annua),which is used in traditional Chinese medicine.Artemisinin and its derivatives(artemisinins)have been widely used f...
关键词:artemisinin inflammation neuroinflammation NEURODEGENERATION Alzheimer’s DISEASE Parkinson’s DISEASE  ANTI-OXIDATION neuroprotection neural regeneration 
Characteristics and advantages of adeno-associated virus vector-mediated gene therapy for neurodegenerative diseases被引量:6
《Neural Regeneration Research》2019年第6期931-938,共8页Yuan Qu Yi Liu Ahmed Fayyaz Noor Johnathan Tran Rui Li 
Common neurodegenerative diseases of the central nervous system are characterized by progressive damage to the function of neurons, even leading to the permanent loss of function. Gene therapy via gene replacement or ...
关键词:nerve REGENERATION central nervous system gene therapy NEURODEGENERATIVE DISEASE viral vector ADENO-ASSOCIATED virus Alzheimer’s DISEASE Parkinson’s DISEASE Huntington’s DISEASE amyotrophic lateral SCLEROSIS spinal muscular atrophy neural REGENERATION 
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