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Gene transfection mediated by polyethyleneiminepolyethylene glycol nanocarrier prevents cisplatininduced spiral ganglion cell damage被引量：1: 《Neural Regeneration Research》2015年第3期425-431,共7页Guan-gui Chen Min Mao Li-zi Qiu Qi-ming Liu; supported by the Natural Science Foundation of Guangdong Province in China,No.S2011040003553; Polyethyleneimine-polyethylene glycol （PEI-PEG）, a novel nanocarrier, has been used for trans- fection and gene therapy in a variety of cells. In our previous study, we successfully carried out PEI-PEG-mediated gene...; 关键词：nerve regeneration polyethyleneimine-polyethylene glycol spiral ganglion cells X-linkedinhibitor of apoptosis protein gene therapy NANOCARRIER cisplatin neural regeneration OTOTOXICITY COCHLEA

Anti-epileptic effects of neuropeptide Y gene transfection into the rat brain被引量：2: 《Neural Regeneration Research》2013年第14期1307-1315,共9页Changzheng Dong Wenqing Zhao Wenling Li Peiyuan Lv Xiufang Dong; Neuropeptide Y gene transfection into normal rat brain tissue can provide gene overexpression, which can attenuate the severity of kainic acid-induced seizures. In this study, a recombinant adeno-associated virus carr...; 关键词：neural regeneration brain injury gene therapy adeno-associated virus neuropeptide Y EPILEPSY N-methyI-D-aspartate receptor kainic acid seizures NEUROREGENERATION

Neuropeptide Y gene transfection inhibits post-epileptic hippocampal synaptic reconstruction被引量：2: 《Neural Regeneration Research》2013年第17期1597-1605,共9页Fan Zhang Wenqing Zhao Wenling Li Changzheng Dong Xinying Zhang Jiang Wu Na Li Chuandong Liang; Exogenous neuropeptide Y has antiepileptic effects; however, the underlying mechanism and optimal administration method for neuropeptide Y are still unresolved. Previous studies have used intracerebroventricular injec...; 关键词：neural regeneration gene therapy neural plasticity NEURODEGENERATION recombinantadeno-associated virus vector neuropeptide Y epilepsy kainic acid synaptic remodeling mossyfiber sprouting hippocampus SYNAPTOPHYSIN NEUROREGENERATION

Nanoparticles carrying neurotrophin-3-modified Schwann cells promote repair of sciatic nerve defects被引量：7: 《Neural Regeneration Research》2013年第14期1262-1268,共7页Haibin Zong Hongxing Zhao Yilei Zhao Jingling Jia Libin Yang Chao Ma Yang Zhang Yuzhen Dong; financially supported by the grants for Science and Technology Innovation Talents in Universities in Ministry of Education of Henan Province in 2010,No.2010HASTIT036; Schwann ceils and neurotrophin-3 play an important role in neural regeneration, but the secretion of neurotrophin-3 from Schwann cells is limited, and exogenous neurotrophin-3 is inactived easily in vivo. In this stud...; 关键词：neural regeneration peripheral nerve injury NEUROTROPHIN-3 nanoparticle liposome Schwanncells sciatic nerve neuroelectrophysiology gene transfection grants-supported paper NEUROREGENERATION

Basic fibroblast growth factor gene transfection in repair of internal carotid artery aneurysm wall: 《Neural Regeneration Research》2012年第36期2915-2921,共7页Lei Jiao Ming Jiang Jinghai Fang Yinsheng Deng Zejun Chen Min Wu; funded by the Key Medical SubjectProject of Jiangsu Province, No. XK2007227; Surgery or interventional therapy has some risks in the treatment of cerebral aneurysm. We established an internal carotid artery aneurysm model by dripping elastase in the crotch of the right internal and external ca...; 关键词：basic fibroblast growth factor LENTIVIRUS ANEURYSM vascular smooth muscle cells hypertension-related gene 1 smooth muscle 22 alpha platelet-derived growth factor gene therapy brain injury neural regeneration

Granulocyte-macrophage colony-stimulating factor-transfected bone marrow stromal cells for the treatment of ischemic stroke被引量：2: 《Neural Regeneration Research》2012年第16期1220-1227,共8页Xingjian Lin Yingdong Zhang Weiguo Liu Jingde Dong Jie Lu Qing Di Jingping Shi; supported by a grant from "135 Project" Foundation of the Public Health Department of Jiangsu Province,China;Nanjing Medical Science and Technique Development Foundation; Adult, male, Sprague-Dawley rats were injected with granulocyte-macrophage colony-stimulating factor-transfected bone marrow stromal cells （GM-CSF-BMSCs） into the ischemic boundary zone at 24 hours after onset of mi...; 关键词：bone marrow stromal cells granulocyte-macrophage colony-stimulating factor gene transfection ischemic stroke TRANSPLANTATION stem cells neural regeneration

Ultrasound microbubbles combined with liposome-mediated pNogo-R shRNA delivery into neural stem cells: 《Neural Regeneration Research》2012年第1期54-59,共6页Weixia Ye Xueping Huang Yangyang Sun Hao Liu Jin Jiang Youde Cao; supported by the Natural Science Foundation of Chongqing (Ultrasound microbubble combining with NgR-RNAi promoted neural stem cells repair of spinal cord injury in rats), No. 2008BB5223; In the present study, ultrasound-mediated microbubble destruction （UMMD） alone and combined with liposome technology was used as a novel nonviral technique to transfect a Nogo receptor （Nogo-R） shRNA plasmid （pNo...; 关键词：ultrasound microbubble LIPOSOME neural stem cell gene transfection Nogo receptor neural regeneration

Brain-derived neurotrophic factor gene transfection promotes neuronal repair and neurite regeneration after diffuse axonal injury被引量：1: 《Neural Regeneration Research》2011年第25期1942-1946,共5页Yin Yu Xingli Zhao Jiajia Shao Qiang Shen Tao Jiang Wei WU Dong Zhu Yu Tian Yongchuan Gu; the National Natural Science Foundation of China (Key Program and General Program), No. 10832012; 10872078; This study sought to assess the potential of brain-derived neurotrophic factor （BDNF） to promote neuronal repair and regeneration in rats with diffuse axonal injury, and to examine the accompanying neurobiological c...; 关键词：diffuse axonal injury brain-derived neurotrophic factor NEURITE gene transfection neural regeneration

Editor's Choice—Adenovirus-mediated gene transfection of stem cells: 《Neural Regeneration Research》2011年第25期1970-1970,共1页; Neural stem cells transplantation plays an important role in repair and cell replacement therapy for nervous system degenerative diseases. However, the self-repair effects are minimal because of a limited absolute num...; 关键词：stem gene Adenovirus-mediated gene transfection of stem cells Editor’s Choice

Oligodendrocyte transcription factor 1 overexpression promotes oligodendrocyte transcription factor 2 expression in the brains of neonatal rats exposed to hypoxia被引量：1: 《Neural Regeneration Research》2011年第34期2713-2717,共5页Lijun Yang Hong Cui Aijun Yang Wenxing Jiang; the National Natural Science Foundation of China, No. 30872778/C1704;the Natural Science Foundation of Beijing, No. 7072023;the Clinical Basic Cooperation Foundation of Capital Medical University, No. 2009jl18;the Clinical Basic Cooperation Foundation of Capital Medical University, No.11JL-L03; To examine the expression profiles of oligodendrocyte transcription factors 1 and 2 （Oligl and Olig2） and the interaction between these two proteins, Oligl was transfected into the lateral ventricles of neonatal rat...; 关键词：oligodendrocyte transcription factor 1 oligodendrocyte transcription factor 2 HYPOXIA neonatal rat gene transfection neural regeneration

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