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  • 期刊=Neural Regeneration Researchx
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p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model被引量：2
《Neural Regeneration Research》2024年第10期2299-2309,共11页Lemeng Feng Chao Wang Cheng Zhang Wulong Zhang Weiming Zhu Ye He Zhaohua Xia Weitao Song 
supported by the National Natural Science Foundation of China,Nos.81974132,81770927;Hunan Provincial Health Commission,No.20220702839;the Natural Science Foundation of Hunan Province of China,No.2022JJ30076;National Key R&D Program of China,No.2021YFA1101202(all to WS)。
Glutamate excitotoxicity has been shown to play an important role in glaucoma, and glutamate can induce ferroptosis. The p38 mitogenactivated protein kinase(MAPK) pathway inhibitor SB202190 has a potential ability to ...
关键词：ferroptosis GLAUCOMA glutamate excitotoxicity p38 MAPK retinal ganglion cell SB202190 
Heat shock factor 1 promotes neurite outgrowth and suppresses inflammation in the severed spinal cord of geckos被引量：1
《Neural Regeneration Research》2023年第9期2011-2018,共8页Bing-Qiang He Ai-Cheng Li Yu-Xuan Hou Hui Li Xing-Yuan Zhang Hui-Fei Hao Hong-Hua Song Ri-Xin Cai Ying-Jie Wang Yue Zhou Yong-Jun Wang 
supported by the National Natural Science Foundation of China,No.31871211 (to YJunW);the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)。
The low intrinsic growth capacity of neurons and an injury-induced inhibitory milieu are major contributo rs to the failure of sensory and motor functional recovery following spinal cord injury.Heat shock transcriptio...
关键词：apoptosis GECKO heat shock factor 1 INFLAMMATION NEURON regeneration spinal cord suppressor of cytokine signaling-3 
Inhibition of microRNA-29b suppresses oxidative stress and reduces apoptosis in ischemic stroke被引量：10
《Neural Regeneration Research》2022年第2期433-439,共7页Yao-Hua Ma Wen-Jing Deng Zhi-Yi Luo Jing Jing Peng-Wei Pan Yao-Bing Yao Yan-Bo Fang Jun-Fang Teng 
MicroRNAs(miRNAs) regulate protein expression by antagonizing the translation of mRNAs and are effective regulators of normal nervous system development, function, and disease. Micro RNA-29 b(mi R-29 b) plays a broad ...
关键词：Akt APOPTOSIS cerebral artery occlusion ischemic stroke MALONDIALDEHYDE microRNA-29b oxidative stress PI3K superoxide dismutase 
Down-regulating Circular RNA Prkcsh suppresses the inflammatory response after spinal cord injury被引量：7
《Neural Regeneration Research》2022年第1期144-151,共8页Jia-Nan Chen Yi-Ning Zhang Li-Ge Tian Ying Zhang Xin-Yu Li Bin Ning 
supported by the National Natural Science Foundation of China,Nos.81771346,82071383;the Taishan Scholar Program of Shandong Province of China,No.tsqn201812156;Spring City Leader Talent Support Plan,No.201984;Rongxiang Regenerative Medicine Foundation of Shandong University,No.2019SDRX-23(all to BN)。
Circular RNAs(circRNAs)are a class of conserved,endogenous non-coding RNAs that are involved in transcriptional and post-transcriptional gene regulation and are highly enriched in the nervous system.They participate i...
关键词：ASTROCYTE Ccl2 ceRNA circRNA inflammation miR-488 NCRNA Prkcsh RNA sequencing spinal cord injury 
Sodium valproate suppresses abnormal neurogenesis induced by convulsive status epilepticus被引量：1
《Neural Regeneration Research》2019年第3期480-484,共5页Peng Wu Yue Hu Xiu-Juan Li Min Cheng Li Jiang 
supported by the National Natural Science Foundation of China for Youth Science Project,No.81201507(to PW)
Status epilepticus has been shown to activate the proliferation of neural stem cells in the hippocampus of the brain, while also causing a large amount of neuronal death, especially in the subgranular zone of the dent...
关键词：nerve REGENERATION status epilepticus sodium valproate long-term POTENTIATION NEURAL stem cells NEUROGENESIS migration subgranular ZONE subventricular ZONE NEURAL REGENERATION 
Genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with Alzheimer's disease被引量：13
《Neural Regeneration Research》2016年第7期1153-1158,共6页Yan Wang Biao Cai Jing Sha Ting-ting Wang Run-ze Cai Chang-ju Ma Tao Han Jun Du 
supported by the National Natural Science Foundation of China,No.81202941;the Key Project Foundation of Oversea Visiting and Research for the Excellent Young and Middle-aged Faculties in Universities of Anhui Province in China,No.gxfx ZD2016119;the Key Project Foundation of Natural Science Research in Universities of Anhui Province in China,No.KJ2016A406
Genistein is effective against amyloid-β toxicity, but the underlying mechanisms are unclear. We hypothesized that genistein may protect neurons by inhibiting the mitochondrial apoptotic pathway, and thereby play a r...
关键词：nerve regeneration GENISTEIN Alzheimer＇s disease MITOCHONDRION apoptosis HIPPOCAMPUS Bax cytochrorne c caspase-3 learning memory neural regeneration 
Cyanidin suppresses amyloid beta-induced neurotoxicity by inhibiting reactive oxygen speciesmediated DNA damage and apoptosis in PC12 cells被引量：3
《Neural Regeneration Research》2016年第5期795-800,共6页Yi Wang Xiao-ting Fu Da-wei Li Kun Wang Xin-zhi Wang Yuan Li Bao-liang Sun Xiao-yi Yang Zun-cheng Zheng Nam Chun Cho 
supported by the Natural Science Foundation of Shandong Province of China,No.ZR2014HM046(to ZCZ)
Amyloid beta（Aβ）-induced oxidative stress is a major pathologic hallmark of Alzheimer＇s disease. Cyanidin, a natural flavonoid compound, is neuroprotective against oxidative damage-mediated degeneration. However, ...
关键词：nerve regeneration CYANIDIN AMYLOID-BETA oxidative damage reactive oxide species APOPTOSIS neural regeneration 
Somatosensory stimulation suppresses the excitability of pyramidal cells in the hippocampal CA1 region in rats被引量：1
《Neural Regeneration Research》2014年第11期1138-1144,共7页Yang Wang Zhouyan Feng Jing Wang Xiaojing Zheng 
supported by Major State Basic Research Development Program of China(973 Program),No.2011CB504400
The hippocampal region of the brain is important for encoding environment inputs and memory formation. However, the underlying mechanisms are unclear. To investigate the behavior of indi-vidual neurons in response to ...
关键词：nerve regeneration somatosensory stimulation tail clamping hippocampal CA1 region local field potential unit spike population spike EXCITABILITY 973 Program neural regeneration 
Baicalin suppresses iron accumulation after substantia nigra injury: relationship between iron concentration and transferrin expression被引量：6
《Neural Regeneration Research》2014年第6期630-636,共7页Chunyan Guo Xin Chen Pei Xiong 
supported by the Scientific Research Common Program of Beijing Municipal Commission of Education,No.KM20110025010
Previous studies have shown that baicalin prevented iron accumulation after substantia nigra injury, reduced divalent metal transporter 1 expression, and increased ferroportin 1 expression in the substantia nigra of r...
关键词：nerve regeneration Parkinson＇s disease iron BAICALIN divalent metal transporter 1 ferroportin 1 DEFEROXAMINE C6 cells the Scientific Research Common Program of Beijing MunicipalCommission of Education neural regeneration 
Survivin small interfering RNA suppresses glioblastoma growth by inducing cellular apoptosis被引量：1
《Neural Regeneration Research》2012年第12期924-931,共8页Yanbo Liu Chunming Miao Zhenjiang Wang Xin He Weigao Shen 
supported by the Natural Science Foundation of Jilin Province,No.2011146,2012150;the Natural Science Foundation of Jilin Technology Division,No.201133139 and 201032235
A survivin small interfering RNA sequence specific for a human and mouse homogenous sequenc~ was constructed. Survivin small interfering RNA could significantly inhibit glioma cell proliferation and induce apoptosis w...
关键词：RNA interference SURVIVIN GLIOBLASTOMA APOPTOSIS 
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