CENTRAL_NERVOUS_SYSTEM

作品数:495被引量:1543H指数:18
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相关作者:陈溪萍陶陆阳秦正红谢强敏陈季强更多>>
相关机构:苏州大学广州医学院第二附属医院浙江大学华中农业大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Human induced pluripotent stem cell-derived therapies for regeneration after central nervous system injury
《Neural Regeneration Research》2025年第11期3063-3075,共13页Stephen Vidman Yee Hang Ethan Ma Nolan Fullenkamp Giles W.Plant 
supported by Ohio State Start Up Fund;National Institutes of Health(NIH);Department of Defense(DoD);Wings for Life Spinal Cord Research Foundation,Wings for Life Spinal Cord Research Foundation(Austria);California Institute of Regenerative Medicine(CIRM);International Spinal Research Trust(United Kingdom);Stanford University Bio-X Program Interdisciplinary Initiatives Seed Grant IIP-7;Dennis Chan Foundation;Klein Family Fund;Lucile Packard Foundation for Children's Health;Stanford Institute for Neuro-Innovation and Translational Neurosciences(SINTN);Saunders Family Neuroscience Fund;James Doty Neurosurgery Fund;Hearst Neuroscience Fund;Eileen Bond Research Fund(to GP)。
In recent years,the progression of stem cell therapies has shown great promise in advancing the nascent field of regenerative medicine.Considering the non-regenerative nature of the mature central nervous system,the c...
关键词:axon regeneration central nervous system regeneration induced pluripotent stem cells NEUROTRAUMA regenerative medicine spinal cord injury stem cell therapy 
Reassessing the AMPK-MTORC1 balance in autophagy in the central nervous system
《Neural Regeneration Research》2025年第11期3209-3210,共2页Marta García-Juan Mario Villa Irene Benito-Cuesta Lara Ordónez-Gutiérrez Francisco Wandosell 
supported by Grants from Spanish FEDER/Science and Innovation Ministry I+D+i-RETOS-PID2021-124801NB-100;Centro de Investigacion Biomedica en Red sobre Enfermedades Neurodegenerativas(CIBERN ED;an initiative of the ISCIII)[PI2016/01];the Fundocion Ramon Areces and Banco Santander to the CBMSO(to FW)。
Autophagy is a cellular degradation and recycling system,indispensable for cellular and organ development,homeostasis,and function.This cellular process is evolutionarily highly conserved to quality control of many pr...
关键词:HOMEOSTASIS SYSTEM hereafter 
Role of resident memory T cells in neuroinflammatory and neurodegenerative diseases in the central nervous system
《Neural Regeneration Research》2025年第11期3227-3228,共2页Kimitoshi Kimura 
The immune system has been attracting increasing attention in the field of chronic neurological disorders in the central nervous system(CNS).Autoreactive T cells targeting CNS antigens play a crucial role in the devel...
关键词:DISEASES DEGENERATIVE PATHOLOGY 
Multilevel analysis of the central-peripheral-target organ pathway:contributing to recovery after peripheral nerve injury
《Neural Regeneration Research》2025年第10期2807-2822,共16页Xizi Song Ruixin Li Xiaolei Chu Qi Li Ruihua Li Qingwen Li Kai-Yu Tong Xiaosong Gu Dong Ming 
supported by grants from the Natural Science Foundation of Tianjin(General Program),Nos.23JCYBJC01390(to RL),22JCYBJC00220(to XC),and 22JCYBJC00210(to QL).
Peripheral nerve injury is a common neurological condition that often leads to severe functional limitations and disabilities.Research on the pathogenesis of peripheral nerve injury has focused on pathological changes...
关键词:central nervous system central peripheral target organ multilevel pathological analysis nerve regeneration peripheral nerve injury peripheral nervous system target organs therapeutic approach 
Mitophagy in acute central nervous system injuries:regulatory mechanisms and therapeutic potentials
《Neural Regeneration Research》2025年第9期2437-2453,共17页Siyi Xu Junqiu Jia Rui Mao Xiang Cao Yun Xu 
supported by the National Natural Science Foundation of China,Nos.81920108017(to YX),82130036(to YX),82371326(to XC),82171310(to XC);the STI2030-Major Projects,No.2022ZD0211800(to YX);Jiangsu Province Key Medical Discipline,No.ZDXK202216(to YX)。
Acute central nervous system injuries,including ischemic stro ke,intracerebral hemorrhage,subarachnoid hemorrhage,traumatic brain injury,and spinal co rd injury,are a major global health challenge.Identifying optimal ...
关键词:autophagy intracerebral hemorrhage ischemic stroke mitochondria mitochondrial biogenesis mitochondrial quality control MITOPHAGY spinal cord injury subarachnoid hemorrhage traumatic brain injury 
Olfactory receptors in neural regeneration in the central nervous system
《Neural Regeneration Research》2025年第9期2480-2494,共15页Rafael Franco Claudia Garrigós Toni Capó Joan Serrano-Marín Rafael Rivas-Santisteban Jaume Lillo 
Olfactory receptors are crucial for detecting odors and play a vital role in our sense of smell,influencing behaviors from food choices to emotional memories.These receptors also contribute to our perception of flavor...
关键词:adenosine receptors adrenergic receptors ectopic expression G proteincoupled receptors GLIA NEURONS 
Interaction of major facilitator superfamily domain containing 2A with the blood-brain barrier
《Neural Regeneration Research》2025年第8期2133-2152,共20页Yilun Ma Taiwei Dong Fei Luan Juanjuan Yang Feng Miao Peifeng Wei 
supported by the National Natural Science Foundation of China,No.82104412(to TD);Shaanxi Provincial Key R&D Program,No.2023-YBSF-165(to TD);the Natural Science Foundation of Shaanxi Department of Science and Technology,No.2018JM7022(to FM);Shaanxi Provincial Key Industry Chain Project,No.2021ZDLSF04-11(to PW)。
The functional and structural integrity of the blood-brain barrier is crucial in maintaining homeostasis in the brain microenvironment;however,the molecular mechanisms underlying the formation and function of the bloo...
关键词:blood-brain barrier(BBB) caveolin-1 central nervous system docosahexaenoic acid endothelial cells LYSOPHOSPHATIDYLCHOLINE major facilitator superfamily domain containing 2A(MFSD2A) TRANSCYTOSIS 
Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders:drug stability,targeting efficiency,and safety
《Neural Regeneration Research》2025年第7期1883-1899,共17页Mingyu Zhang Chunyu Xiang Renrui Niu Xiaodong He Wenqi Luo Wanguo Liu Rui Gu 
supported by the National Natural Science Foundation of China, Nos. 82271411 (to RG), 51803072 (to WLiu);grants from the Department of Finance of Jilin Province, Nos. 2022SCZ25 (to RG), 2022SCZ10 (to WLiu), 2021SCZ07 (to RG);Jilin Provincial Science and Technology Program, No. YDZJ202201ZYTS038 (to WLiu);The Youth Support Programmed Project of China-Japan Union Hospital of Jilin University, No. 2022qnpy11 (to WLuo);The Project of China-Japan Union Hospital of Jilin University, No. XHQMX20233 (to RG)
Various nanoparticle-based drug delivery systems for the treatment of neurological disorders have been widely studied.However,their inability to cross the blood–brain barrier hampers the clinical translation of these...
关键词:Alzheimer's disease amyotrophic lateral sclerosis brain tumors central nervous system Huntington's disease liposome drug delivery neurological disorders Parkinson's disease spinal cord injury traumatic brain injury 
The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases
《Neural Regeneration Research》2025年第6期1582-1598,共17页Yanxi Li Jing Xue Yuejia Ma Ke Ye Xue Zhao Fangliang Ge Feifei Zheng Lulu Liu Xu Gao Dayong Wang Qing Xia 
supported by the Natural Science Foundation of Heilongjiang Province of China,Outstanding Youth Foundation,No.YQ2022H003 (to DW)。
N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis a...
关键词:Alzheimer's disease cell self-renewal central nervous system MEMORY MICROGLIA nerve regeneration neurodegenerative diseases NEUROGENESIS RNA methylation 
Harnessing therapeutic potential of induced pluripotent stem cell–derived endothelial cells for remyelination in the central nervous system
《Neural Regeneration Research》2025年第6期1715-1716,共2页Dan Ma Nona Pop 
supported by a grant from Aston University,Birmingham,UK (to DM)。
Myelin is the protective sheath surrounding nerve fibers, and its damage(demyelination) occurs in many central nervous system(CNS) diseases, including multiple sclerosis(MS), traumatic injury, neurodegenerative diseas...
关键词:MYELIN protective DISEASES 
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