云南高校图书馆联盟文献共享服务平台- CHROMATIN

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Uncovering chromatin accessibility and cancer diagnostic potential via cell-free DNA utilization: 《Science Bulletin》2024年第19期2987-2992,共6页Jie Li Jiahui Chen Xin Sun Heli Yang Keyong Sun Chang Liu Yongwang Wang Mengyue Xu Xin Ji Ji Zhang Xiaojiang Wu Anqiang Wang Biao Fan Xiaolu Zhang Yue Wu Peilin Cui Junya Peng Yupei Zhao Wenming Wu Honghao Yu Zhaode Bu Jiafu Ji Xun Lan; supported by Beijing Natural Science Foundation(Z190022);the National Natural Science Foundation of China(81972680,82141102,52271254,82072748,82141102,and 82072748);a start-up fund from Tsinghua University-Peking University Joined Center for Life Science,Guangxi One Thousand Young and Middle-Aged College and University Backone Teachers Cultivation Program,the CAMS Innovation Fund for Medical Sciences(2021-12M-1-002 and 2023-12M-2-002);the National High Level Hospital Clinical Research Funding(2022-PUMCH-D-001,2022-PUMCH-A-082);the National Key Research and Development Program of China(2020YFA0803702);the Science Foundation of Peking University Cancer Hospital(PY202330).; Gene expression patterns of tumor cells can be inferred from features of circulating cell-free DNA(cfDNA),such as histone modifications and fragmentation patterns at promoters.However,the direct relationship between c...; 关键词：diagnosis CANCER ALONE

Single-cell RNA-seq and chromatin accessibility profiling decipher the heterogeneity of mouseγδT cells被引量：5: 《Science Bulletin》2022年第4期408-426,M0004,共20页Zhenhua Li Quanli Yang Xin Tang Yiming Chen Shanshan Wang Xiaojie Qi Yawen Zhang Zonghua Liu Jing Luo Hui Liu Yongbing Ba Lianxia Guo Baojian Wu Fang Huang Guangchao Cao Zhinan Yin; supported by the National Natural Science Foundation of China(31830021,32030036,32000615,and 32100695);the National Key Research and Development Program of China(2020YFA0803502);the 111 Project(B16021);China Postdoctoral Science Foundation(2020M683180,2019M663374,and 2020T130251);Guangdong Basic and Applied Basic Research Foundation(2020A1515111045 and 2020A1515111081)。; The distinct characteristics ofγδT cells determine their vital roles in the formation of local immune responses and contribute to tissue homeostasis.However,the heterogeneity ofγδT cells across tissues remains unc...; 关键词：γδT cell scRNA-seq scATAC-seq Innate immunity HETEROGENEITY

You are never alone: crosstalk among epigenetic players: 《Science Bulletin》2015年第10期899-904,I0007,共7页王承志朱冰; supported by the Chinese Ministry of Science and Technology(2015CB856200 and 2011CB965300);the National Natural Science Foundation of China(91419305 and31425013);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB08010103);the Howard Hughes Medical Institute International Early Career Scientist Program; Different cell types in a certain organism contain the same genome while running diverse transcription programs. This is controlled by epigenetic information, including DNA modifications, histone modifications, histon...; 关键词：EPIGENETICS CROSSTALK CHROMATIN Histone modification DNA methylation

Roles of histones and nucleosomes in gene transcription: 《Chinese Science Bulletin》2001年第3期184-188,共5页Baiqu Huang Qinhua Zeng Xiaohui Bi Yuhong Wang Yuxin Li; Part of the work in this article was supported by the National Natural Science Foundation of China (Grant No. 3997038) ;and the National "973" Basic Research Project (Grant No. G19I99053902).; This article reviews the latest research developments in the field of eukaryotic gene regulation by the structural alterations of chromatin and nucleosomes. The following issues are briefly addressed: (i) nucleosome a...; 关键词：HISTONES NUCLEOSOME CHROMATIN REMODELING gene transcription.

Folding patterns of chromatin in chicken erythrocyte studied by using AFM and TEM: 《Chinese Science Bulletin》1998年第4期289-291,共3页Liu, ZX Zhou, MY Xie, HY Qian, RL Zhang, Y Hu, J Li, MQ; ThisworkwassupportedbytheFoundationofChineseAcademyofSciences (GrantNo .KJ95 1_Al_6 0 3)andShanghaiOpenLaboratoryofLifeSciences.; Four folding patterns (～15, ～30-40, ～60 and ～90-110 nm) of the higher_order structure of chromatin in chicken erythrocytes have been observed with an atomic force microscope (AFM) under near natural conditions. Re...; 关键词：CHROMATIN structure NUCLEUS of CHICKEN ERYTHROCYTE AFM TEM.

FORCING INTERCELLULAR CYTOPLASM AND CHROMATIN MIGRATION BETWEEN THE MERISTEMTIC CELLS OF Pinellia ternate AND Commelina communis BY LB TECH NIQUE AND THE SUBSEQUENT REGENERATION OF HYBRID PLANTS: 《Chinese Science Bulletin》1992年第4期350-350,共1页崔亚亚陈毅平吴伯骥; The interfamilical hybrid plants with color character for genetic marker of Pinellia ternate and Commelina communis have been obtained successfully by the LB technique——forcing intercellular cytoplasm and chromatin ...; 关键词：Pinellia ternate communis INTERCELLULAR MIGRATION MOTIVE preliminary CYTOPLASM marker OSMOTIC

PROGRESS IN STUDIES OF CHROMOSOMAL SCAFFOLD: 《Chinese Science Bulletin》1990年第9期705-711,共7页郝水; A considerable progress has been made in studies of chromatin and chromosome ultrastructure during the past fifteen years or so. The discovery of nucleosomes as the basic units of eukaryotic chromatin and chromosomes ...; 关键词：chromosomes ULTRASTRUCTURE CHROMOSOMAL PROGRESS EUKARYOTIC stained silver nitrate accounted CHROMATIN

ADP-RIBOSYL TRANSFERASE INHIBITORS POTENTIATING THE ANTITUMOR ACTIVITY OF PEPLOMYCIN: 《Chinese Science Bulletin》1988年第3期236-240,共5页陈海英潘启超; ADP-ribosyl transferase (ADPRT)transfers the ADP-ribose portion of NAD to either chromatin protein or another ADP-ribose molecule, to form polymer of (ADP-R)_n. This process is involved in many cellular biofunctions. ...; 关键词：RIBOSE repair ANTITUMOR inhibit HEPATOMA alone portion markedly transfers CHROMATIN

THE FORMATION OF MICROTUBULES BY THE CHROMATIN OF THE ISOLATED NUCLEI WITH BROKEN NUCLEAR MEMBRANE: 《Chinese Science Bulletin》1984年第1期100-103,共4页严缘昌施履吉; It has been known that in the population of isolated interphasie nuclei, there are always some nuclei with broken nuclear membrane among the intact ones. Taking advantage of this fact, we may find out whether there ar...; 关键词：NUCLEI TUBULIN nucleus INTACT ORGANIZING broken matin details centers Pellet

ISOLATION AND CHARACTERIZATION OF CHROMOSOMAL HMG PROTEINS FROM PEA: 《Chinese Science Bulletin》1982年第8期880-883,共4页徐典朋杨中汉; An extract from chromatin with 0.35 M NaCl is a heterogenous class of nonhistone chromosomal proteins. On the basis of their respective electrophoretic mobilities in polyacrylamide gel, the 0.35 M NaCl extract is divi...; 关键词：CHROMOSOMAL POLYACRYLAMIDE latter respective CHROMATIN wheat Proteins residues concentrated AMMONIUM

CHROMATIN