CHOLINERGIC

作品数：112被引量：321H指数：9
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The dual role of striatal interneurons:circuit modulation and trophic support for the basal ganglia被引量：3
《Neural Regeneration Research》2024年第6期1277-1283,共7页Elliot Wegman Marlena Wosiski-Kuhn Yu Luo 
Striatal interneurons play a key role in modulating striatal-dependent behaviors,including motor activity and reward and emotional processing.Interneurons not only provide modulation to the basal ganglia circuitry und...
关键词：CHOLINERGIC dopamine GABAERGIC INTERNEURON levodopa-induced dyskinesia PARVALBUMIN sonic hedgehog STRIATUM trophic factor 
A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson's disease被引量：2
《Neural Regeneration Research》2024年第2期324-330,共7页Xi Chen Yuhu Zhang 
supported by the National Natural Science Foundation of China,No.82071419;Key Research and Development Program of Guangzhou,No.202206010086;High-level Hospital Construction Project,No.DFJH201907;Supporting Research Funds for Outstanding Young Medical Talents in Guangdong Province,No.KJ012019442(all to YZ)。
The dichotomized brain system is a concept that was generalized from the‘dual syndrome hypothesis’to explain the heterogeneity of cognitive impairment,in which anterior and posterior brain systems are independent bu...
关键词：anterior brain system CEREBELLUM CHOLINERGIC cognitive impairment DOPAMINERGIC dual syndrome hypothesis neuroimage NEUROTRANSMITTER Parkinson’s disease posterior brain system therapeutic targets 
Emerging non-invasive therapeutic approaches targeting hypocholinergic neural systems in Parkinson's disease
《Neural Regeneration Research》2023年第4期809-810,共2页Nicolaas I.Bohnen Alison J.Yarnall 
supported by the National Institute of Health,No.P50 NS123067;The Farmer Family Foundation;supported by the NIHR Newcastle Biomedical Research Centre(BRC);The NIHR BRC is a partnership between Newcastle Hospitals NHS Foundation Trust and Newcastle University;funded by the National Institute for Health and Care Research(NIHR)。
Cholinergic system associated DOPA-refractory motor and cognitive symptoms-a need for novel therapeutic approaches:Accumulating evidence points to significant motor and non-motor morbidities associated with hypocholin...
关键词：CHOLINERGIC THERAPEUTIC DRUGS 
Neurotrophin receptors,gamma-secretase inhibitors,and neurodegeneration of basal forebrain cholinergic neurons
《Neural Regeneration Research》2022年第7期1493-1494,共2页Marçal Vilar 
supported by the Spanish Minister of Economy and Competitiveness grant SAF2017-84096-R;by the Generalitat Valenciana 2018-55,to MV。
The amyloid hypothesis of Alzhemer’s disease(AD)postulates that the generation of amyloid-beta(Aβ)peptide from the amyloid precursor protein(APP)by the action of theγ-secretase complex is one of the principal cause...
关键词：AMYLOID AΒ CHOLINERGIC 
Dopaminergic-cholinergic imbalance in movement disorders: a role for the novel striatal dopamine D2-muscarinic acetylcholine M1 receptor heteromer
《Neural Regeneration Research》2021年第7期1406-1408,共3页RenéA.J.Crans Francisco Ciruela 
supported by the Fonds Wetenschappelijk Onderzoek(FWOSBO, Grant number 140028);Ministerio de Ciencia, Innovación y Universidades-Agencia Estatal de Investigación/FEDER(Grant number SAF2017-87349-R);Generalitat de Catalunya(Grant numbers 2017 SGR1604 and 2017 SGR595);Fundació la Marató de TV3(grant number 20152031);supported by an FWO Travel Grant for a Long Stay Abroad(grant number V420718N);an EMBO Short-Term Fellowship(grant number 6735)。
The striatum is the primary input structure of the basal ganglia, which participates in motivational and goaldirected behaviors(Pisani et al., 2007).In physiological conditions, local cholinergic interneurons(ChIs) an...
关键词：al. DOPAMINE DOPAMINE 
Schwann-like adipose-derived stem cells as a promising therapeutic tool for peripheral nerve regeneration:effects of cholinergic stimulation被引量：1
《Neural Regeneration Research》2021年第6期1218-1220,共3页Roberta Piovesana Alessandro Faroni Ada Maria Tata Adam J.Reid 
supported by Ateneo Sapienza Funds 2017(RM11715C7F959CA4);“Avvio Giovani”Project 2018(AR11816435A0F81D)from Ateneo Sapienza to RP.RP fellowship was also supported by CIB 2018;AF and AJR are supported by the Hargreaves and Ball Trust,the Academy of Medical Sciences(AMS-SGCL7);by Seed Corn Funding from the Rosetrees Trust and the Stoneygate Trust(M746).
Schwann-like adipose-derived stem cells and nerve injury:Peripheral nerve injuries(PNIs)are a common clinical problem usually as a consequence of trauma.Despite optimal surgical management,PNI has a lifelong impact on...
关键词：STIMULATION INJURIES PARALYSIS 
Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process被引量：9
《Neural Regeneration Research》2021年第1期58-67,共10页Mariana Toricelli Arthur Antonio Ruiz Pereira Guilherme Souza Abrao Helena Nascimento Malerba Julia Maia Hudson Sousa Buck Tania Araujo Viel 
MT received studentship from Sao Paulo Research Foundation(2017/21655-6);HSB was a Brazilian National Council for Scientific and Technological Development researcher(425838/2016-1,307252/2017-5);This work was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior–Brasil(CAPES)–Finance Code 001 and FAPESP(2016/07115-6).
Aging is a dynamic and progressive process that begins at conception and continues until death.This process leads to a decrease in homeostasis and morphological,biochemical and psychological changes,increasing the ind...
关键词：cell senescence cell signaling CHOLINERGIC enriched environment long-term potentiation NEURODEGENERATION NEUROGENESIS neuroinflammatory neuronal death NEUROPROTECTION neurotophin 
Kai Xin San ameliorates scopolamine-induced cognitive dysfunction被引量：13
《Neural Regeneration Research》2019年第5期794-804,共11页Yu-Min Xu Xin-Chen Wang Ting-Ting Xu Hong-Ying Li Shang-Yan Hei Na-Chuan Luo Hong Wang Wei Zhao Shu-Huan Fang Yun-Bo Chen Li Guan Yong-Qi Fang Shi-Jie Zhang Qi Wang Wei-Xiong Liang 
supported by the National Natural Science Foundation of China,No.81473740,81673627,81673717(to QW);Guangzhou Science Technology and Innovation Commission Technology Research Projects,China,No.2018050100(to QW);the Foundation for Characteristic Innovation of Educational Commission of Guangdong Province,China,Grant No.2016KTSCX011(to SHF);the Open Tending Project for Construction of High-Level University,Guangzhou University of Chinese Medicine,China,No.34 and 118,2017(to SHF);the Technology Platform of Clinical Trials on New Traditional Medicine,China,No.2012ZX09303009-003(to WXL);the Technology Platform of Clinical Evaluation on New Traditional Medicine,China,No.2008ZX09312-021(to WXL)
Kai Xin San(KXS, containing ginseng, hoelen, polygala, and acorus), a traditional Chinese herbal compound, has been found to regulate cognitive dysfunction; however, its mechanism of action is still unclear. In this s...
关键词：Kai Xin SAN cognitive DYSFUNCTION SCOPOLAMINE hydrobromide neuroprotection oxidative stress SYNAPTIC DYSFUNCTION apoptosis CHOLINERGIC system DYSFUNCTION DONEPEZIL neural regeneration 
Effects of repetitive transcranial magnetic stimulation on cognitive function and cholinergic activity in the rat hippocampus after vascular dementia被引量：36
《Neural Regeneration Research》2018年第8期1384-1389,共6页Xiao-Qiao Zhang Li Li Jiang-Tao Huo Min Cheng Lin-Hong Li 
supported by a grant from the Major Project of Educational Commission of Hubei Province of China,No.D20152101
Repetitive transcranial magnetic stimulation （rTMS） is a non-invasive treatment that can enhance the recovery of neurological function after stroke. Whether it can similarly promote the recovery of cognitive functio...
关键词：nerve regeneration cholinergic system neurotrophic factor hippocampal CA1 region learning and memory function repetitivetranscranial magnetic stimulation vascular dementia neural regeneration 
Neuroprotection of N-benzylcinnamide on scopolamine-induced cholinergic dysfunction in human SH-SY5Y neuroblastoma cells被引量：2
《Neural Regeneration Research》2017年第9期1492-1498,共7页Nicha Puangmalai Wipawan Thangnipon Rungtip Soi-ampornkul Nirut Suwanna Patoomratana Tuchinda Saksit Nobsathian 
supported by a joint Mahidol University and The Thailand Research Fund(TRF)grant(IRG5780009);TRF Royal Golden Jubilee Ph.D.Program(grant No.PHD/0175/2552);the Office of the Higher Education Commission,Ministry of Education,Thailand
Alzheimer＇s disease, a progressive neurodegenerative disease, affects learning and memory resulting from cholinergic dysfunction. Scopolamine has been employed to induce Alzheimer＇s disease-like pathology in vivo an...
关键词：Alzheimer＇s disease ACETYLCHOLINE apoptosis acetylcholinesterase inhibitor oxidative stress N-benzylcinnamide natural product SCOPOLAMINE neuronal regeneration 
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